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Article
Open AccessPrevalence and factors associated with dyslipidemia in patients with first hospitalization for major depressive disorder: a large sample cross-sectional study
Major depressive disorder (MDD) is a severe mental illness with high relapse rates and high mortality. Depression not only severely limits psychosocial functioning but also reduces quality of life. It can also...
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Article
The role of venture capitalists in reward-based crowdfunding: a game-theoretical analysis
Most entrepreneurs seek VC funding after the reward-based crowdfunding campaign succeeds, and venture capitalists (VCs) can contribute to the project in two aspects: investment and operational expertise. With ...
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Article
Financing the newsvendor with vendor credit line
Vendor credit line ( \(VCL\) VCL ) is a common instrument...
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Article
Open AccessJoint advertising and ordering decisions under the pre-sales crowdfunding
Our study considers a company launching new product on pre-sales crowdfunding platform and explores the joint advertising and ordering decisions in mass market thereafter. Under the “AON” mechanism, we constru...
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Article
Open AccessGender differences in prevalence and associated factors of metabolic syndrome in first-treatment and drug-naïve schizophrenia patients
Metabolic syndromes (MetS) are clinical syndromes involving multiple pathological states with distinct gender-specific clinical patterns. As a serious disorder associated with psychiatric conditions, the preva...
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Article
Open AccessUSP10 deubiquitinates Tau, mediating its aggregation
Normal Tau promotes the assembly and stabilization of microtubules, thus, maintaining axon transport. In Alzheimer’s disease (AD), Tau aggregation causes it to lose these above-mentioned functions. However, th...
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Article
Open AccessDefective mitophagy and the etiopathogenesis of Alzheimer’s disease
Accumulation of impaired mitochondria and energy metabolism disorders are non-negligible features of both aging and age-related neurodegeneration, including Alzheimer’s disease (AD). A growing number of studie...
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Article
Open AccessAltered fecal microbiota composition in individuals who abuse methamphetamine
As a severe public health problem, methamphetamine (METH) abuse places a heavy burden on families and society. A growing amount of evidence has indicated communication between gut microbiota and the CNS in dru...
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Article
Open AccessInfluence of social isolation caused by coronavirus disease 2019 (COVID-19) on the psychological characteristics of hospitalized schizophrenia patients: a case-control study
Coronavirus disease 2019 (COVID-19) has been classified as a pandemic, and mental hospitals located in epidemic centers have been affected. Social isolation is an important and irreplaceable measure to control...
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Article
Open AccessEmergency response strategy for containing COVID-19 within a psychiatric specialty hospital in the epicenter of the COVID-19 epidemic in China
Coronavirus disease 2019 (COVID-19) has been recognized as a global pandemic, and psychiatric institutions located in the epicenter of the epidemic in China are facing severe challenges in fighting the epidemi...
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Article
ω-3PUFAs Improve Cognitive Impairments Through Ser133 Phosphorylation of CREB Upregulating BDNF/TrkB Signal in Schizophrenia
Schizophrenia (SZ) is a serious mental condition and is associated with cognitive impairments. Brain-derived neurotrophic factor (BDNF) is one of the learning- and memory-related molecules found in the CNS and...
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Article
Open AccessExpression of P301L-hTau in mouse MEC induces hippocampus-dependent memory deficit
Intracellular accumulation of abnormally phosphorylated tau in different types of neurons is a pathological characteristic of Alzheimer’s disease (AD). While tau modification and associated neuronal loss and h...
