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Article
Open AccessBacterial processing of glucose modulates C. elegans lifespan and healthspan
Intestinal microbiota play an essential role in the health of a host organism. Here, we define how commensal Escherichia coli (E. coli) alters its host after long term exposure to glucose using a Caenorhabditis e...
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Article
Correction: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
Nature 513, 110–114 (2014); doi:10.1038/nature13441 corrigendum Nature 519, 118 (2015); doi:10.1038/nature14149 In Extended Data Fig. 1b of this Letter, the photomicrographic images of the hepatoblast cells gr...
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Article
Correction: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
Nature 513, 110–114 (2014); doi:10.1038/nature13441 In this Article, the last line of the Acknowledgements should read: J.M.L. and D.S. are supported by the Asociación Española Contra el Cáncer (AECC); this ha...
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Article
Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
Gain-of-function mutations in isocitrate dehydrogenase (IDH) are among the most common genetic alterations in intrahepatic cholangiocarcinoma (IHCC), a deadly cancer of the liver bile ducts; now mutant IDH is sho...