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Article
Structural features of GmIRCHS, candidate of the I gene inhibiting seed coat pigmentation in soybean: implications for inducing endogenous RNA silencing of chalcone synthase genes
Most commercial soybean varieties have yellow seeds due to loss of pigmentation in the seed coat. The I gene inhibits pigmentation over the entire seed coat, resulting in a uniform yellow color of mature harveste...
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Article
Hepatoid carcinoma of the skin: spontaneous rat skin hepatoid carcinoma with eosinophilic globules and crystals immunoreactive to α-1-antitrypsin
We present a case of hepatoid carcinoma of the abdominal skin in a male Wistar rat. Histopathologically, this carcinoma resembled human hepatocellular carcinoma with respect to trabecular-sinusoidal structures...
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Article
Recombinant production and evaluation of an antibacterial l-amino acid oxidase derived from flounder Platichthys stellatus
Fish produce mucus substances as a defensive outer barrier against several bacterial infections. We have recently identified an antibacterial l-amino acid oxidase (psLAAO1) in the mucus layer of the flounder Plat...
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Article
Antibacterial properties of l-amino acid oxidase: mechanisms of action and perspectives for therapeutic applications
Venom, the mucus layer covering the body surface, ink glands, mammary glands, milk, and various animal secretory functions as both a physical and chemical defense barrier against bacteria and virus infections....
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Article
Rapid isolation of murine primary hepatocytes for chromosomal analysis
Primary hepatocyte culture is a crucial tool for investigations of liver function and for evaluating the toxic effects of drugs. In addition, chromosomal analysis of hepatocytes could also prove useful for und...
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Article
Radiation-induced bystander effect in large Japanese field mouse (Apodemus speciosus) embryonic cells
Although evidence suggests that ionizing radiation can induce the bystander effect (radiation-induced bystander effect: RIBE) in cultured cells or mouse models, it is unclear whether the effect occurs in cells...
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Article
Open AccessFirst report of the isolation of Balamuthia mandrillaris in the northern region of Japan
Balamuthia mandrillaris is a free-living amoeba that lives in soil and water near human settlements. B. mandrillaris was first isolated from a mandrill baboon that died at the San Diego Zoo Wildlife Park in Calif...
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Article
Open AccessRadiation-Induced Bystander Effect is Mediated by Mitochondrial DNA in Exosome-Like Vesicles
Exosome-like vesicles (ELV) are involved in mediating radiation-induced bystander effect (RIBE). Here, we used ELV from control cell conditioned medium (CCCM) and from 4 Gy of X-ray irradiated cell conditioned...
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Article
Metal coordination by L-amino acid oxidase derived from flounder Platichthys stellatus is structurally essential and regulates antibacterial activity
L-amino acid oxidases (LAAOs) have antibacterial activity and play important roles in innate immunity. We have previously identified a LAAO of ~52 kDa in size from the mucus layer of the flounder Platichthys stel...
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Article
Antimicrobial properties of L-amino acid oxidase: biochemical features and biomedical applications
Mucus layer that covers the body surface of various animal functions as a defense barrier against microbes, environmental xenobiotics, and predators. Previous studies have reported that L-amino acid oxidase (L...
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Reform Impact and Underlying Factors: A Changing Policymaking Process and Changing Education Policies in Japan
This chapter charts political changes to the Japanese education policy making process, by analyzing the relative relations and power between four main actors: the ruling and opposition parties in the Diet, inf...
