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Open AccessPublisher Correction: NDUFS4 regulates cristae remodeling in diabetic kidney disease
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Open AccessNDUFS4 regulates cristae remodeling in diabetic kidney disease
The mitochondrial electron transport chain (ETC) is a highly adaptive process to meet metabolic demands of the cell, and its dysregulation has been associated with diverse clinical pathologies. However, the ro...
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Open AccessNovel urinary glycan profiling by lectin array serves as the biomarkers for predicting renal prognosis in patients with IgA nephropathy
In IgA nephropathy (IgAN), IgA1 molecules are characterized by galactose deficiency in O-glycans. Here, we investigated the association between urinary glycosylation profile measured by 45 lectins at baseline and...
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Nondiabetic Renal Disease (NDRD) and Diabetic Kidney Disease (DKD)
Recently, clinicopathological features in diabetic kidney disease (DKD) are getting more complicated and heterogeneous. In general, renal biopsy in patients with diabetes is performed to differentiate from non...
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Open AccessGut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease
Diabetic kidney disease is a major cause of renal failure that urgently necessitates a breakthrough in disease management. Here we show using untargeted metabolomics that levels of phenyl sulfate, a gut microb...
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Article
Open AccessCyst infection in autosomal dominant polycystic kidney disease: penetration of meropenem into infected cysts
Cyst infection is a common and serious complication of autosomal dominant polycystic kidney disease (ADPKD) that is often refractory. Carbapenems are frequently needed to treat to patients with refractory cyst...
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Article
Nationwide multicenter kidney biopsy study of Japanese patients with hypertensive nephrosclerosis
Nephrosclerosis is an increasingly reason for dialysis in Japan. However, kidney biopsy specimens for hypertensive nephrosclerosis are very limited; thus, the pathologic evaluation of hypertensive nephrosclero...
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Clinicopathological analysis of biopsy-proven diabetic nephropathy based on the Japanese classification of diabetic nephropathy
The Japanese classification of diabetic nephropathy reflects the risks of mortality, cardiovascular events and kidney prognosis and is clinically useful. Furthermore, pathological findings of diabetic nephropa...
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Article
TAFRO syndrome with refractory thrombocytopenia responding to tocilizumab and romiplostim: a case report
Thrombocytopenia, anasarca, fever, reticulin fibrosis, organomegaly (TAFRO) syndrome is a unique clinicopathologic subtype of multicentric Castleman’s disease that has recently been identified in Japan. Howeve...
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A clinical staging score to measure the severity of dialysis-related amyloidosis
The ongoing effort to prevent dialysis-related amyloidosis (DRA) has been hampered by lack of any way to measure DRA’s severity. Yet, such measurement is essential for assessing the effect of DRA treatment. Ac...
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Survival after arterial embolization therapy in patients with polycystic kidney and liver disease
Transcatheter arterial embolization (TAE) has become a therapeutic option for symptomatic polycystic kidney disease (PKD) and polycystic liver disease (PLD). However, factors affecting survival with renal TAE ...
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Open AccessUmbilical hernia in autosomal dominant polycystic kidney disease
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IgG4-Related Disease and Malignant Tumor
IgG4-related disease (IgG4-RD) is considered to be a benign disease responsive to glucocorticoid therapy, but recently cases complicated by malignant tumors have been described. The potential association betwe...
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Article
Open AccessQuality of life of patients with ADPKD—Toranomon PKD QOL study: cross-sectional study
The quality of life (QOL) of patients with autosomal dominant polycystic kidney disease (ADPKD) has not been investigated well. This study was performed to clarify the QOL of patients with ADPKD and to identif...
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Open AccessLong term follow up of congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) on hemodialysis for 19 years: a case report
Thrombotic thrombocytopenic purpura (TTP) is frequently associated with renal abnormalities, but there have been few reports about renal abnormalities in patients with hereditary TTP. In particular, little is ...
