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  1. Article

    Three CAG Trinucleotide Repeats on Chromosome 6 (D6S1014, D6S1015, and D6S1058) Are Not Expanded in 30 Families with Schizophrenia

    Since 1991, more than five neuro-genetic disorders have been recognized to be caused by trinucleotide repeat expansions, and the list of such diseases should grow. The diseases are characterized clinically by ...

    Koichi Ohara MD, Ph.D, Kunihiko Tani MD, Toshio Tsukamoto MD in Neuropsychopharmacology (1997)

  2. Article

    Analysis of the 5′-Flanking Promoter Region of the 5-HT2A Receptor Gene in Schizophrenia

    We studied the 5′-flanking promoter region comprising positions −1441 to +128 of the 5-HT2A receptor gene in 95 schizophrenics and 100 unrelated normal control subjects. The genes encoding the 5-HT2A receptor exo...

    Koichi Ohara MD, Ph.D, Atsuchi Ino BL, Tatsuya Ishigaki MD, Ph.D in Neuropsychopharmacology (1997)

  3. Article

    Intact 5-HT2A Receptor Exons and the Adjoining Intron Regions in Schizophrenia

    Genes that regulate serotonergic (5-HT) systems may underlie the etiology of schizophrenia. In this study the gene encoding the 5-HT2A receptor in schizophrenics and healthy controls was examined. First, we seque...

    Tatsuya Ishigaki MD, Dar-Win **e MD, Ph.D, Jian-Cheng Liu MD in Neuropsychopharmacology (1996)