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Article
Open AccessAnxiolytic effects of Enterococcus faecalis 2001 on a mouse model of colitis
Ulcerative colitis (UC) is a refractory inflammatory bowel disease, which is known to cause psychiatric disorders such as anxiety and depression at a high rate in addition to peripheral inflammatory symptoms. ...
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Article
Open AccessActivation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice
Angiotensin (Ang)-converting-enzyme (ACE) 2 converts Ang II into Ang (1–7), which in turn acts on MAS receptors (ACE2/Ang (1–7)/MAS receptors pathway). This pathway has neuroprotective properties, making it a ...
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Article
Open AccessReorganization of the ancestral sex-determining regions during the evolution of trioecy in Pleodorina starrii
The coexistence of three sexual phenotypes (male, female and bisexual) in a single species, ‘trioecy’, is rarely found in diploid organisms such as flowering plants and invertebrates. However, trioecy in haplo...
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Article
Open AccessSmall grant subsidy application effects on productivity improvement: evidence from Japanese SMEs
This study examines the effects of a small grants subsidy on small- and medium-sized enterprises’ (SMEs) productivity. Using rich Japanese firm-level data, we analyze the effects of both applying for and recei...
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Article
Open AccessTemporal change in Syndecan-1 as a therapeutic target and a biomarker for the severity classification of COVID-19
Coronavirus disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure is associated with high mortality. The pathogenesis of COVID-19 is associated with microembolism or microvascular endo...
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Article
Establishment of human airway epithelial cells with doxycycline-inducible cell growth and fluorescence reporters
We previously reported the successful establishment of multiple immortalized cell lines that preserved the original nature of the primary cells via co-expression of R24C mutant cyclin-dependent kinase 4 (CDK4R24C
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Chapter and Conference Paper
A Web-Based Attendance Management System with NFC Seat Identifiers
We present a web-based system for managing student attendance by exploiting the capability of NFC tag to invoke the web browser to access the URL written in the tag. Suppose an NFC tag sticker is pasted at eac...
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Article
Evaluation of primer pairs for studying arbuscular mycorrhizal fungal community compositions using a MiSeq platform
Although many primers have been proposed for arbuscular mycorrhizal fungi (AMF)–specific sequencing, only a few studies have evaluated suitable primer pairs for MiSeq analysis. Here, we analyzed AMF community ...
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Article
Peculiarities of biofilm formation by Paracoccus denitrificans
Most bacteria form biofilms, which are thick multicellular communities covered in extracellular matrix. Biofilms can become thick enough to be even observed by the naked eye, and biofilm formation is a tightly...
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Article
Open AccessEffect of Enterococcus faecalis 2001 on colitis and depressive-like behavior in dextran sulfate sodium-treated mice: involvement of the brain–gut axis
Patients with inflammatory bowel disease (IBD), including those with ulcerative colitis and Crohn’s disease, have higher rates of psychiatric disorders, such as depression and anxiety; however, the mechanism o...
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Article
Alterations in behavioral responses to dopamine agonists in olfactory bulbectomized mice: relationship to changes in the striatal dopaminergic system
Olfactory bulbectomy (OBX) in rodents is considered a putative animal model of depression. It has been reported that some abnormal behaviors observed in this animal model of depression involve dopaminergic neu...
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Chapter and Conference Paper
Exploiting No-SQL DB for Implementing Lifelog Mashup Platform
To support efficient integration of heterogeneous lifelog service, we have previously proposed and implemented a lifelog mashup platform consisting of the lifelog common data model (LLCDM) and the lifelog mashup ...
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Chapter
Stress Distribution of the Spinal Cord and Clinical Relevance in Cervical Spondylotic Myelopathy
Intramedullary stress was analyzed in patients with cervical spondylotic myelopathy (CSM) using a finite element method (FEM). A total of 99 disc levels of 30 patients with CSM were analyzed and divided into...
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Article
Effects of low and high levels of moderate hypoxia on anaerobic energy release during supramaximal cycle exercise
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Article
Effects of low and high levels of moderate hypoxia on anaerobic energy release during supramaximal cycle exercise
The purpose of this study was to investigate whether hypoxia can alter anaerobic energy release during supramaximal exercise. Seven male subjects performed 12 submaximal cycling tests to establish the relation...