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Article
Photostability evaluation of manidipine tablets and structural determination of its photoproducts
Manidipine (MP) is a dihydropyridine drug, which is treated for the reduction of high blood pressure. The aim of this study is to clarify the photochemical behavior of MP in the case of ultraviolet light (UV) ...
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Article
The evaluation of photochemical behavior of antihistaminic drug triprolidine in an aqueous media
Photodegradation is widely known as a changer of both the quality and the quantity of several chemical compounds. In this study, we sought to examine the photochemical behavior of triprolidine (TRP), which is ...
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Article
Photodegradation profiling of nitrendipine: evaluation of active pharmaceutical ingredient, tablets and its altered forms
Nitrendipine (NTR) is a dihydropyridine drug, which is well-known as a photodegradable pharmaceutical. However, the photochemical reaction of NTR has not been evaluated in detail from now. In this study, we pe...
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Article
Phospholipid analysis of two influenza A virus-infected cell lines differing in their viral replication kinetics
Fluctuations in phospholipid composition in infected cells during influenza A virus replication were analyzed using two different susceptible host cell lines: H292 cells, exhibiting a rapid cytopathic effect, ...
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Article
Open AccessStructure determination of clinofibrate photoproducts generated by ultraviolet-light irradiation in aqueous media
Photodegradation of clinofibrate, which is one of the fibrate drugs, was evaluated and chemical structures of its photoproducts were determined. Clinofibrate in aqueous media was photodegraded gradually by the...
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Article
Open AccessTopological unification of time-reversal and particle-hole symmetries in non-Hermitian physics
Topological phases are enriched in non-equilibrium open systems effectively described by non-Hermitian Hamiltonians. While several properties unique to non-Hermitian topological systems were uncovered, the fun...
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Article
Abnormalities in the Metabolism of Fatty Acids and Triacylglycerols in the Liver of the Goto-Kakizaki Rat: A Model for Non-Obese Type 2 Diabetes
The Goto-Kakizaki (GK) rat is widely used as an animal model for spontaneous-onset type 2 diabetes without obesity; nevertheless, little information is available on the metabolism of fatty acids and triacylgly...
