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  1. Article

    Open Access

    Feasibility study of an intervention program to enhance self-confidence of kindergarten teachers who deal with radiation-related health concerns from parents with young children

    Following the Fukushima Daiichi Nuclear Power Station accident in March 2011, radiation anxiety was high among residents in affected areas. Enhancing radiation-related health literacy is effective in reducing ...

    Nobuaki Moriyama, Chihiro Nakayama, Kiyotaka Watanabe in Pilot and Feasibility Studies (2022)

  2. Article

    Open Access

    A new non-invasive graphical method for quantification of cerebral blood flow with[ \(^{123}\hbox {I}\) ] IMP

    [ \(^{123}\hbox {I}\) ...

    Masashi Kameyama, Kiyotaka Watanabe in Annals of Nuclear Medicine (2018)

  3. No Access

    Article

    Analysis of the binding of bovine and human fibrinogen to ferritin: evidence that fibrinogen is a common ferritin-binding protein in mammals

    Both human and horse fibrinogen are heme-binding proteins, and horse fibrinogen also exhibits heme-mediated ferritin binding. This study found that bovine and human fibrinogen are heme-mediated ferritin-bindin...

    Akiko Okada, Yasunaga Yoshikawa, Kiyotaka Watanabe, Koichi Orino in BioMetals (2015)

  4. Article

    Open Access

    Reduced canine BRCA2 expression levels in mammary gland tumors

    Mammary tumors are the most common tumor type in intact female dogs. Recently, the breast cancer 2 early onset (BRCA2) gene was proposed to be associated with tumorigenesis in dogs. The expression level of BRCA2 ...

    Yasunaga Yoshikawa, Masami Morimatsu, Kazuhiko Ochiai in BMC Veterinary Research (2015)

  5. Article

    Open Access

    The presence of heat-labile factors interfering with binding analysis of fibrinogen with ferritin in horse plasma

    Horse fibrinogen has been identified as a plasma specific ferritin-binding protein. There are two ways in the binding of ferritin-binding protein with ferritin: one is direct binding and the other is indirect ...

    Kazuma Takahashi, Takashi Kondo, Yasunaga Yoshikawa in Acta Veterinaria Scandinavica (2013)

  6. Article

    Open Access

    Quantifying longitudinal right ventricular dysfunction in patients with old myocardial infarction by using speckle-tracking strain echocardiography

    We investigated longitudinal right ventricular (RV) function assessed using speckle-tracking strain echocardiography in patient with myocardial infarction (MI), and identified the contributing factors for RV d...

    Katsuhisa Konishi, Kaoru Dohi, Muneyoshi Tanimura, Yuichi Sato in Cardiovascular Ultrasound (2013)

  7. Article

    Open Access

    Echocardiographic estimation of pulmonary capillary wedge pressure using the combination of diastolic annular and mitral inflow velocities

    We aimed to identify the clinical utility of a simple echocardiographic approach for estimating the pulmonary capillary wedge pressure (PCWP) on the basis of the combined assessment of mitral inflow and tissue...

    Tadafumi Sugimoto, Kaoru Dohi, Masaki Tanabe in Journal of Echocardiography (2013)

  8. No Access

    Article

    Iron-dependent binding of bovine milk α-casein with holo-lactoferrin, but not holo-transferrin

    Bovine milk α-casein has been identified as an iron- and heme-binding protein. However, the physiological role of its iron-binding remains to be elucidated in more detail. α-Casein was immobilized on CNBr-acti...

    Naoko Shibuya, Yasunaga Yoshikawa, Kiyotaka Watanabe, Hiromichi Ohtsuka in BioMetals (2012)

  9. Article

    Open Access

    Establishment of a PCR analysis method for canine BRCA2

    Mammary tumors are the most common tumor type in both human and canine females. In women, carriers of mutations in BRCA2, a tumor suppressor gene product, have a higher risk of breast cancer. Canine BRCA2 has als...

    Yasunaga Yoshikawa, Masami Morimatsu, Kazuhiko Ochiai, Kento Okuda in BMC Research Notes (2012)

  10. No Access

    Article

    Effect of diquat-induced oxidative stress on iron metabolism in male Fischer-344 rats

    Diquat toxicity causes iron-mediated oxidative stress; however, it remains unclear how diquat affects iron metabolism. Here, we examined the effect of diquat-induced oxidative stress on iron metabolism in male...

    Masashi Higuchi, Yasunaga Yoshikawa, Koichi Orino, Kiyotaka Watanabe in BioMetals (2011)

  11. No Access

    Article

    Heme-mediated binding of α-casein to ferritin: evidence for preferential α-casein binding to ferrous iron

    Bovine milk α-casein was identified as a ferritin-binding protein, and ferritin is known to be a heme-binding protein. In this study, we found that the binding of α-casein to bovine spleen ferritin in vitro wa...

    Aya Usami, Masakazu Tanaka, Yasunaga Yoshikawa, Kiyotaka Watanabe in BioMetals (2011)

  12. No Access

    Article

    Characterization of feline serum ferritin-binding proteins: the presence of a novel ferritin-binding protein as an inhibitory factor in feline ferritin immunoassay

    Ferritin-binding proteins (FBPs) such as anti-ferritin antibody, α-2-macroglobulin, apolipoprotein B are expected to interact with circulating ferritin to eliminate it from circulation. However, we found that ...

    Hirofumi Sakamoto, Tomomi Kuboi, Takahiko Nagakura, Sayako Hayashi in BioMetals (2009)

  13. Article

    Open Access

    Sequence analysis of dolphin ferritin H and L subunits and possible iron-dependent translational control of dolphin ferritin gene

    Iron-storage protein, ferritin plays a central role in iron metabolism. Ferritin has dual function to store iron and segregate iron for protection of iron-catalyzed reactive oxygen species. Tissue ferritin is ...

    Azusa Takaesu, Kiyotaka Watanabe, Shinji Takai in Acta Veterinaria Scandinavica (2008)

  14. No Access

    Article

    Apolipoprotein B binds ferritin by hemin-mediated binding: evidence of direct binding of apolipoprotein B and ferritin to hemin

    Apolipoprotein B (apoB) is known to be a ferritin-binding protein. Here we show that apoB binds to ferritin through hemin-mediated binding. Human apoB bound to bovine spleen, horse spleen, and canine liver fer...

    Takenori Seki, Tomoya Kunichika, Kiyotaka Watanabe, Koichi Orino in BioMetals (2008)

  15. No Access

    Article

    Relationship between body iron stores and diquat toxicity in male Fischer-344 rats

    The effects of body iron stores on diquat (DQ)-induced toxicity were examined in male Fischer-344 rats, which are sensitive to this herbicide. The rats (5 weeks old) were fed diets containing 40 (lower iron st...

    Teruhisa Abe, Takasuke Kinda, Yasushi Takano, Seishiro Chikazawa in Biometals (2006)

  16. No Access

    Article

    Purification and Characterization of Canine Serum Ferritin-binding Proteins

    Ferritin-binding protein (FBP) is known to interact with circulating ferritins in mammals. Canine FBPs were purified from canine serum by affinity chromatography and were identified as IgM, IgG, and IgA by imm...

    Koichi Orino, Maki Uehara, Shozo Okano, Kiyotaka Watanabe in Biometals (2006)

  17. No Access

    Chapter and Conference Paper

    Video Synthesis with High Spatio-Temporal Resolution Using Motion Compensation and Image Fusion in Wavelet Domain

    This paper presents a novel algorithm for obtaining a high spatio-temporal resolution video from two video sequences. These sequences are high resolution with low frame rate and low resolution with high frame ...

    Kiyotaka Watanabe, Yoshio Iwai, Hajime Nagahara in Computer Vision – ACCV 2006 (2006)

  18. No Access

    Chapter and Conference Paper

    Video Synthesis with High Spatio-temporal Resolution Using Spectral Fusion

    We propose a novel strategy to obtain a high spatio-temporal resolution video. To this end, we introduce a dual sensor camera that can capture two video sequences with the same field of view simultaneously. Th...

    Kiyotaka Watanabe, Yoshio Iwai in Multimedia Content Representation, Classif… (2006)

  19. No Access

    Article

    Kinetic analysis of bovine spleen apoferritin and recombinant H and L chain homopolymers: Iron uptake suggests early stage H chain ferroxidase activity and second stage L chain cooperation

    Ferritin utilizes ferroxidase activity to incorporate iron. Iron uptake kinetics of bovine spleen apoferritin were compared with those of recombinant H chain ferritin and L chain ferritin homopolymers. H chain...

    Koichi Orino, Satoshi Harada, Masahiro Natsuhori, Kazuaki Takehara in Biometals (2004)

  20. No Access

    Article

    Clearance rates of biotinylated ferritins in canine: A possible physiological role of canine serum ferritin as an iron transporter

    To elucidate the physiological role of canine serum ferritin, we measured clearance rates of biotinylated ferritins in beagle. Biotinylated canine tissue ferritins were cleared rapidly from circulation. The cl...

    Koichi Orino, Ayumi Terada, Akiko Yoshida, Shozo Okano, Seiichi Higuchi in Biometals (2003)

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