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Article
Photoreaction products of extract from the fruiting bodies of Polyozellus multiplex
Photochemical reactions are powerful tools for synthesizing organic molecules. The input of energy provided by light offers a means to produce strained and unique molecules that cannot be assembled using therm...
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Article
Correction: Inhibition of Aβ aggregation by naphtho-γ-pyrone derivatives from a marine-derived fungus, Aspergillus sp. MPUC239
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Article
Enniatins from a marine-derived fungus Fusarium sp. inhibit biofilm formation by the pathogenic fungus Candida albicans
Candidemia is a life-threatening disease common in immunocompromised patients, and is generally caused by the pathogenic fungus Candida albicans. C. albicans can change morphology from yeast to hyphae, forming bi...
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Article
Inhibition of Aβ aggregation by naphtho-γ-pyrone derivatives from a marine-derived fungus, Aspergillus sp. MPUC239
Alzheimer’s disease (AD) is an important human disease that mainly causes cognitive impairments. Growing evidence has shown that amyloid-β (Aβ) peptide plays a key role in AD pathogenesis in what is known as t...
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Article
Amyloid β aggregation inhibitory activity of triterpene saponins from the cactus Stenocereus pruinosus
Six new triterpene saponins (1–5,7) and 3 known saponins (6,8,9) were isolated from MeOH extracts of the cactus Stenocereus pruinosus. The structures of the isolated saponins were elucidated using MS, IR, and com...
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Article
Triterpenoid saponins from Polaskia chichipe Backbg. and their inhibitory or promotional effects on the melanogenesis of B16 melanoma cells
Five new oleanane-type saponins 1–5 together with a known saponin 6 and a steroidal glycoside 7 were isolated from Polaskia chichipe Backbg., and their structures were determined from their 1D and 2D NMR and HRFA...
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Article
A novel nucleoside from the edible mushroom, Tricholoma japonicum
A novel nucleoside, 9-β-d-ribopyranosylpurine (2), along with three known nucleosides, adenosine (1), uridine (3) and nebularine (4), were isolated from the edible mushroom, Tricholoma japonicum. The structure of...
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Article
Anti-angiogenic effect of α-mangostin
Eleven known prenyl xanthones, isolated from the pericarp of Garcinia mangostana, were tested for their ability to inhibit the phosphorylation of kinase domain receptor (KDR) tyrosine kinase. α-Mangostin was foun...
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Article
Phenolic compounds from Cryptocarya konishii: their cytotoxic and tyrosine kinase inhibitory properties
Two chalcone derivatives, 2′-hydroxychalcone (1) and desmethylinfectocaryone (2), together with five known phenolic compounds infectocaryone (3), cryptocaryone (4), kurzichalcolactone A (5), pinocembrin (6) and t...
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Article
Antioxidant activity of red pigments from the lichens Lethariella sernanderi, L. cashmeriana, and L. sinensis
A yellow and new dark red pigments were isolated from Lethariella sernanderi, L. cashmeriana, and L. sinensis as antioxidant components. The yellow pigment was identified as canarione (1), and the others were det...
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Article
New triterpene saponins from Stenocereus eruca (Cactaceae)
Two new triterpene saponins, named stellatoside B (1) and erucasaponin A (2), were isolated from a cactaceous plant, Stenocereus eruca A. C. Gibson & K. E. Horak (Machaerocereus eruca Br. & R.). The structures of...
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Article
Triterpenoid saponins from cultural plants of Stenocereus stellatus (Cactaceae)
A new triterpenoid saponin, named stellatoside A (1), and a known saponin (2), were isolated from cultural plants of the cactus Stenocereus stellatus (Ludwig G. K. Pfeiffer) V. Riccobono. The structure of 1 was d...
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Article
The impairing effects of chaetochromin D on mitochondrial respiration and structure
Chaetochromin D, a toxic secondary metabolite ofChaetomlum graclle, was examined for impairing effects on mitochondrial respiration and structure (swelling-induction) using isolated rat liver mitochondria to gain...
