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    Continuous-Flow Left Ventricular Assist Device Support Improves Myocardial Supply:Demand in Chronic Heart Failure

    Continuous-flow left ventricular assist devices (CF LVADs) are rotary blood pumps that improve mean blood flow, but with potential limitations of non-physiological ventricular volume unloading and diminished v...

    Kevin G. Soucy, Carlo R. Bartoli, Dustin Phillips in Annals of Biomedical Engineering (2017)

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    Apical-Ventricular Cannula for Aortic Valve Bypass Therapy

    A growing number of elderly patients with significant co-morbidities do not meet the inclusion criteria for conventional cardiac surgical therapies, including aortic valve replacement and mechanical circulator...

    Kevin G. Soucy, Joel D. Graham in Cardiovascular Engineering and Technology (2013)

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    Single exposure to radiation produces early anti-angiogenic effects in mouse aorta

    Radiation exposure can increase the risk for many non-malignant physiological complications, including cardiovascular disease. We have previously demonstrated that ionizing radiation can induce endothelial dys...

    Kevin G. Soucy, David O. Attarzadeh in Radiation and Environmental Biophysics (2010)

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    Single exposure gamma-irradiation amplifies xanthine oxidase activity and induces endothelial dysfunction in rat aorta

    Irradiation of the heart and vasculature can cause a spectrum of cardiovascular complications, including increased risk of myocardial infarction or coronary heart disease. Although irradiation is implicated in...

    Kevin G. Soucy, Hyun Kyo Lim, Alexandre Benjo in Radiation and Environmental Biophysics (2007)