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  1. Article

    Open Access

    Function and anatomy of plant siRNA pools derived from hairpin transgenes

    RNA interference results in specific gene silencing by small-interfering RNAs (siRNAs). Synthetic siRNAs provide a powerful tool for manipulating gene expression but high cost suggests that novel siRNA product...

    Bess L Chau, Kevin AW Lee in Plant Methods (2007)

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    Article

    An hsRPB4/7-dependent yeast assay for trans-activation by the EWS oncogene

    Chromosomal fusions of the N-terminal region of the Ewings Sarcoma Oncogene (EWS-Activation-Domain, EAD) to the DNA-binding domains of a variety of cellular transcription factors, produce oncogenic proteins (EWS-...

    Huiqing Zhou, Kevin AW Lee in Oncogene (2001)

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    Article

    The EWS/ATF1 fusion protein contains a dispersed activation domain that functions directly

    Naturally occurring chromosomal fusion of the Ewings Sarcoma Oncogene (EWS) to distinct cellular transcription factors, produces aberrant transcriptional activators that function as dominant oncogenes. In Mali...

    Shu Pan, Koh Yee Ming, Theresa A Dunn, Kim KC Li, Kevin AW Lee in Oncogene (1998)

  4. No Access

    Article

    MMSP tumor cells expressing the EWS/ATF1 oncogene do not support cAMP-inducible transcription

    Malignant Melanoma of Soft Parts (MMSP) is associated with the EWS/ATF1 fusion protein that arises due to chromosomal fusion of the Ewings Sarcoma oncogene (EWS) and the cellular transcription factor ATF1. EWS...

    Kim KC Li, Kevin AW Lee in Oncogene (1998)