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  1. Article

    Open Access

    Deletion of GPR81 activates CREB/Smad7 pathway and alleviates liver fibrosis in mice

    Enhanced glycolysis is a crucial metabolic event that drives the development of liver fibrosis, but the molecular mechanisms have not been fully understood. Lactate is the endproduct of glycolysis, which has r...

    Ying Zhi, Kerui Fan, Shuang Liu, Kai Hu, **nyan Zan, Ling Lin… in Molecular Medicine (2024)

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  2. Article

    Open Access

    Highlighting Water-Bearing Zones in Tunnel by Inverse Wavefield Transform of TEM Data

    Transient electromagnetic method (TEM) is an effective tool to map the groundwater distribution in tunnel construction. To highlight the structural information of the water-bearing zones, inverse wavefield tra...

    Gang Wang, Neng Wang, **n zheng, Kerui Fan in Geotechnical and Geological Engineering (2024)

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  3. Article

    Open Access

    Negative regulation of pro-apoptotic AMPK/JNK pathway by itaconate in mice with fulminant liver injury

    Accumulating evidence indicates that metabolic responses are deeply integrated into signal transduction, which provides novel opportunities for the metabolic control of various disorders. Recent studies sugges...

    Kerui Fan, Kun Chen, **nyan Zan, Ying Zhi, Xue Zhang, **nyue Zhang… in Cell Death & Disease (2023)

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  4. No Access

    Article

    Cross-Hole Radar Fractures Detection of Tunnel Side Wall Based on Full Waveform Inversion and Reverse Time Migration

    Cross-hole radar is a method for geophysical exploration of geological conditions between two holes that can meet the need for refined detection of fractures. Full waveform inversion and reverse time migration...

    Fahe Sun, Jiaxing Wang, Chuanyi Ma, Wenhan Li… in Geotechnical and Geological Engineering (2022)