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  1. Article

    Open Access

    Transvaginal extraperitoneal single-port laparoscopic sacrocolpopexy for apical prolapse after total/subtotal hysterectomy: Chinese surgeons’ initial experience

    To introduce a novel technique of transvaginal extraperitoneal single-port laparoscopic sacrocolpopexy (ESLS) for apical prolapse and to evaluate the feasibility and short-term outcomes of this technique.

    Zhiying Lu, Yisong Chen, Chengzhen **ao, Keqin Hua, Changdong Hu in BMC Surgery (2024)

  2. Article

    Open Access

    Association of preoperative conization with recurrences after laparoscopic radical hysterectomy for FIGO 2018 stage IB1 cervical cancer

    To evaluate association of preoperative conization with recurrences after laparoscopic radical hysterectomy (LRH) for FIGO 2018 stage IB1 cervical cancer.

    Yan Ding, Xuyin Zhang, Junjun Qiu, Chunbo Li in Archives of Gynecology and Obstetrics (2023)

  3. Article

    Open Access

    Impacts of ovarian preservation on the prognosis of neuroendocrine cervical carcinoma: a retrospective analysis based on machine learning

    Neuroendocrine cervical carcinoma (NECC) is a rare but aggressive malignancy with younger patients compared to other common histology types. This study aimed to evaluate the impacts of ovarian preservation (OP...

    Xuesong **ang, Yunqiang Zhang, Keqin Hua in World Journal of Surgical Oncology (2023)

  4. No Access

    Article

    LncRNA-LA16c-313D11.11,A Signature to Predict Endometrial Carcinoma Patients with a Better Survival

    The aim of this study was to develop and internally validate a nomogram of the probability EC patients surviving longer than 5 years. Quantitative real-time PCR (qRT–PCR) was implemented to analyze the express...

    Xue Ding, Song** Liu, Na Liu, Keqin Hua, Weijuan **n in Reproductive Sciences (2023)

  5. No Access

    Article

    Comparison of Sheares vaginoplasty, vaginoplasty using acellular porcine small intestinal submucosa graft and laparoscopic peritoneal vaginoplasty in patients with Mayer-Rokitansky-Küster-Hauser syndrome

    The aim of this study is to compare the perioperative, anatomical and functional outcomes of patients with Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS), undergoing Sheares vaginoplasty, vaginoplasty using a...

    Qi Zhou, Xuyin Zhang, Yanyun Li, Keqin Hua in International Urogynecology Journal (2023)

  6. No Access

    Article

    Comparison of two different methods for cervicovaginal reconstruction: a long-term follow-up

    As a consequence of the evolution of surgery in reconstructive techniques, cervicovaginal reconstruction has become an option for patients diagnosed with congenital cervical and vaginal atresia. This study was...

    **aotong Liu, **gxin Ding, Yuqi Li, Keqin Hua in International Urogynecology Journal (2023)

  7. No Access

    Article

    Transvaginal natural orifice transluminal endoscopic surgery for presacral–uterosacral ligament compound suspension in apical compartment prolapse

    We aimed to describe a novel mesh-free pelvic repair surgery for apical prolapse and to evaluate the effect of this technique and early outcomes.

    **aojuan Wang, Kinji Arikawa, Junwei Li, Keqin Hua in International Urogynecology Journal (2023)

  8. Article

    Open Access

    Single-cell transcriptomics reveals cellular heterogeneity and molecular stratification of cervical cancer

    Cervical cancer (CC) is the most common gynecological malignancy, whose cellular heterogeneity has not been fully understood. Here, we performed single-cell RNA sequencing (scRNA-seq) to survey the transcripto...

    Chunbo Li, Hao Wu, Luopei Guo, Danyang Liu, Shimin Yang in Communications Biology (2022)

  9. Article

    Open Access

    A novel Silva pattern-based model for precisely predicting recurrence in intermediate-risk cervical adenocarcinoma patients

    Considering the unique biological behavior of cervical adenocarcinoma (AC) compared to squamous cell carcinoma, we now lack a distinct method to assess prognosis for AC patients, especially for intermediate-ri...

    Chenyan Guo, **ang Tao, Lihong Zhang, Ying Zhang, Keqin Hua in BMC Women's Health (2022)

  10. No Access

    Article

    Evaluating tissue-engineered repair material for pelvic floor dysfunction: a comparison of in vivo response to meshes implanted in rats

    Achieving better anatomic restoration and decreasing the associated complications are necessary for material repair of pelvic floor dysfunction (PFD). This study was aimed to investigate host response to tissu...

    **aojuan Wang, Yisong Chen, Zhongyong Fan, Keqin Hua in International Urogynecology Journal (2022)

  11. Article

    Open Access

    Integrated in silico analysis of LRP2 mutations to immunotherapy efficacy in pan-cancer cohort

    Immunotherapy has emerged as a novel therapy, while many patients are refractory. Although, several biomarkers have been identified as predictive biomarkers for immunotherapy, such as tumor specific genes, PD-...

    Chunbo Li, Yan Ding, Xuyin Zhang, Keqin Hua in Discover Oncology (2022)

  12. Article

    Open Access

    Reproductive and postsurgical outcomes of infertile women with deep infiltrating endometriosis

    This study aimed to summarize and analyze clinical characteristics and reproductive outcomes in postoperative deep infiltrating endometriosis (DIE).

    Ning Zhang, Shugen Sun, Yunxi Zheng, **aofang Yi, Junjun Qiu in BMC Women's Health (2022)

  13. Article

    Open Access

    Transvaginal single-port versus multi-port laparoscopic sacrocolpopexy: a retrospective cohort study

    Sacrocolpopexy is the gold standard treatment for apical prolapse. With the development of minimally invasive surgical techniques, the new approach of transvaginal single-port laparoscopic sacrocolpopexy (TS-L...

    Junwei Li, Yizhen Sima, Changdong Hu, **aojuan Wang, Zhiying Lu, Keqin Hua in BMC Surgery (2022)

  14. Article

    Psychological intervention in women with Mayer-Rokitansky-Küster-Hauser syndrome after artificial vaginoplasty: a prospective study

    The negative psychological impact on women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is long-lasting, resulting from not only the disease itself, but also the cumbersome and painful treatment process...

    Shuyi Shao, **ao Wang, **aohong Lei, Keqin Hua in International Urogynecology Journal (2022)

  15. Article

    Open Access

    Two-dimensional and three-dimensional T2 weighted imaging-based radiomic signatures for the preoperative discrimination of ovarian borderline tumors and malignant tumors

    Ovarian cancer is the most women malignancy in the whole world. It is difficult to differentiate ovarian cancers from ovarian borderline tumors because of some similar imaging findings.Radiomics study may help...

    Xuefen Liu, Tian** Wang, Guofu Zhang, Keqin Hua, Hua Jiang in Journal of Ovarian Research (2022)

  16. Article

    Open Access

    Long-term outcomes of transvaginal mesh surgery for pelvic organ prolapse: a retrospective cohort study

    The objective of this study was to evaluate the overall outcomes and complications of transvaginal mesh (TVM) placement for the management of pelvic organ prolapse (POP) with different meshes with a greater th...

    **aojuan Wang, Yisong Chen, Changdong Hu, Keqin Hua in BMC Women's Health (2021)

  17. Article

    Open Access

    Vaginal-assisted gasless laparoendoscopic single-site radical hysterectomy for early cervical cancer: a retrospective pilot study

    Minimally invasive surgery for early cervical cancer is debated. We developed this new vaginal-assisted gasless laparoendoscopic single-site radical hysterectomy for early cervical cancer, and we aimed to eval...

    **aojuan Wang, Junwei Li, Keqin Hua, Yisong Chen in World Journal of Surgical Oncology (2021)

  18. Article

    Open Access

    Transvaginal natural orifice transluminal endoscopic surgery for uterosacral ligament suspension: pilot study of 35 cases of severe pelvic organ prolapse

    To describe the short-term outcomes of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) for uterosacral ligament suspension (USLS) in patients with severe prolapse.

    Zhiying Lu, Yisong Chen, **aojuan Wang, Junwei Li, Keqin Hua, Changdong Hu in BMC Surgery (2021)

  19. No Access

    Article

    Transvaginal single-port laparoscopic pelvic reconstruction with Y-shaped mesh: experiences of 93 cases

    To demonstrate the outcomes of pelvic reconstruction using Y-shaped mesh in patients with multiple-compartment pelvic organ prolapse via transvaginal single-port laparoscopy.

    Junwei Li, Changdong Hu, **aojuan Wang, Keqin Hua in International Urogynecology Journal (2021)

  20. Article

    Open Access

    Transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy for uterus weighing ≥1 kg

    The transvaginal natural orifice transluminal endoscopic surgery (vNOTES) applied in gynecology has been developed recent years and been evolving. In this study, we aimed to evaluate the feasibility and effect...

    **aojuan Wang, Junwei Li, Keqin Hua, Yisong Chen in BMC Surgery (2020)

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