3 Result(s)
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Article
Open AccessADAR1 RNA editing enzyme regulates R-loop formation and genome stability at telomeres in cancer cells
ADAR1 is involved in adenosine-to-inosine RNA editing. The cytoplasmic ADAR1p150 edits 3’UTR double-stranded RNAs and thereby suppresses induction of interferons. Loss of this ADAR1p150 function underlies the ...
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Article
Open AccessRadiation-Induced Bystander Effect is Mediated by Mitochondrial DNA in Exosome-Like Vesicles
Exosome-like vesicles (ELV) are involved in mediating radiation-induced bystander effect (RIBE). Here, we used ELV from control cell conditioned medium (CCCM) and from 4 Gy of X-ray irradiated cell conditioned...
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Article
Dynamic landscape and regulation of RNA editing in mammals
Using the GTEx data and others, a comprehensive analysis of adenosine-to-inosine RNA editing in mammals is presented; targets of the various ADAR enzymes are identified, as are several potential regulators of ...
