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Chapter
Nanofiber Extracellular Matrices in Regenerative Medicine
Stem cells hold great potential for application in regenerative medicine and drug discovery. For these applications, stem cells need to be expanded by induced differentiation; these expanded stem cells need to...
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Article
Three-dimensional cultured liver-on-a-Chip with mature hepatocyte-like cells derived from human pluripotent stem cells
Liver-on-a-Chip technology holds considerable potential for applications in drug screening and chemical-safety testing. To establish such platforms, functional hepatocytes are required; however, primary hepato...
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Article
3D printing of soft lithography mold for rapid production of polydimethylsiloxane-based microfluidic devices for cell stimulation with concentration gradients
Three-dimensional (3D) printing is advantageous over conventional technologies for the fabrication of sophisticated structures such as 3D micro-channels for future applications in tissue engineering and drug s...
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Article
Integrated microfluidic devices for combinatorial cell-based assays
The development of miniaturized cell culture platforms for performing parallel cultures and combinatorial assays is important in cell biology from the single-cell level to the system level. In this paper we de...
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Article
A microfluidic platform for sequential ligand labeling and cell binding analysis
Develo** biochemical and cell biological assay for screening biomolecules, evaluating their characteristics in biological processes, and determining their pharmacological effects represents a key technology ...