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Open AccessSurvival outcomes in locally advanced dMMR rectal cancer: surgery plus adjunctive treatment vs. surgery alone
Recent studies have shown that deficient mismatch repair (dMMR) rectal cancer may be related to treatment resistance, resulting in a worse prognosis than proficient MMR (pMMR) rectal cancer. The purpose of thi...
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Article
Open AccessStage III deficient mismatch repair colon patients get greater benefit from earlier starting oxaliplatin-based chemotherapy regimen
We evaluate the prognostic value of chemotherapy and other prognostic factors on overall survival among colon patients with deficient mismatch repair (dMMR), and determine the optimum time to start chemotherap...
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Article
Open AccessEffects of deficient mismatch repair on the prognosis of patients with stage II and stage III colon cancer during different postoperative periods
We evaluated the prognostic role of deficient mismatch repair (dMMR) systems in stage II and stage III colon cancer patients during different postoperative periods. We also assessed whether patients aged ≥75 c...
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Article
Open AccessClinicopathological and prognostic value of SIRT6 in patients with solid tumors: a meta-analysis and TCGA data review
In addition to its role in cellular progression and cancer, SIRT6, a member of nicotinamide adenine dinucleotide (NAD+)-dependent class III deacylase sirtuin family, serves a variety of roles in the body's immune...
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Article
Open AccessHigher titer hepatitis B core antibody predicts a higher risk of liver metastases and worse survival in patients with colorectal cancer
There have been controversial voices on if hepatitis B virus infection decreases the risk of colorectal liver metastases or not. This study aims to the find the association between HBV infection and postoperat...
