Skip to main content

8 Result(s)

within Kellie L. K. Tamashiro Remove this filter

and

  1. Article

    Open Access

    Maternal High-Fat Diet Induces Long-Lasting Defects in Bone Structure in Rat Offspring Through Enhanced Osteoclastogenesis

    Maternal stressors during the prenatal and perinatal periods are associated with increased susceptibility for and severity of chronic disease phenotypes in adult offspring. In this study, we used a rat model o...

    Priyanka Kushwaha, Seva G. Khambadkone, Mengni Li… in Calcified Tissue International (2021)

    Download PDF (4598 KB) View Article

  2. No Access

    Article

    Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

    Huntington's disease is a neurodegenerative disease caused by the accumulation of mutant htt protein. Now, two groups led by Dimitri Krainc and Wenzhen Duan report that mutant htt binds and inactivates the dea...

    Mali Jiang, Jiawei Wang, **rong Fu, Lin Du, Hyunkyung Jeong, Tim West… in Nature Medicine (2012)

  3. No Access

    Article

    A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice

    Given the contribution of cortisol dysregulation to neuropsychiatric and metabolic disorders, it is important to be able to accurately compute glucocorticoid burden, a measure of allostatic load. One major pro...

    Richard S. Lee, Kellie L. K. Tamashiro, **aoju Yang, Ryan H. Purcell… in Psychopharmacology (2011)

  4. No Access

    Chapter

    Developmental, Behavioral, and Physiological Phenotype of Cloned Mice

    Cloning from adult somatic cells has been successful in at least ten species. Although generating viable cloned mammals from adult cells is technically feasible, prenatal and perinatal mortality is high and li...

    Kellie L. K. Tamashiro, Randall R. Sakai, Yukiko Yamazaki… in Somatic Cell Nuclear Transfer (2007)

  5. No Access

    Article

    The impact of moderate daily alcohol consumption on aggression and the formation of dominance hierarchies in rats

    Group-housed male rats form social hierarchies, and under these conditions, it has been reported that subordinate (SUB) rats consume more alcohol than dominant (DOM) rats. We tested the hypothesis that a histo...

    Elizabeth A. Duncan, Kellie L. K. Tamashiro, Mary M. N. Nguyen… in Psychopharmacology (2006)

  6. No Access

    Article

    Cloned mice have an obese phenotype not transmitted to their offspring

    Mammalian cloning using somatic cells has been accomplished successfully in several species, and its potential basic, clinical and therapeutic applications are being pursued on many fronts. Determining the lon...

    Kellie L.K. Tamashiro, Teruhiko Wakayama, Hidenori Akutsu… in Nature Medicine (2002)

  7. No Access

    Article

    Cloning of mice to six generations

    Mice have been cloned by nuclear transfer into enucleated oocytes1,2,3, and here we describe the reiterative cloning of mice to four and six generations in two independent lines. Successive generations showed no ...

    Teruhiko Wakayama, Yoichi Shinkai, Kellie L. K. Tamashiro, Hiroyuki Niida… in Nature (2000)

  8. No Access

    Article

    Bypassing Spermiogenesis for Several Generations Does Not Have Detrimental Consequences on the Fertility and Neurobehavior of Offspring: A Study Using the Mouse

    Purpose: This study was conducted to determine whether the omission of spermiogenesis and all prefertilization events for five generations in mice affects the fertility or behavio...

    Kellie L. K. Tamashiro, Yasuyuki Kimura… in Journal of Assisted Reproduction and Genet… (1999)