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    Open Access

    pyDarwin machine learning algorithms application and comparison in nonlinear mixed-effect model selection and optimization

    Forward addition/backward elimination (FABE) has been the standard for population pharmacokinetic model selection (PPK) since NONMEM® was introduced. We investigated five machine learning (ML) algorithms (Gene...

    **nnong Li, Mark Sale, Keith Nieforth… in Journal of Pharmacokinetics and Pharmacody… (2024)

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