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Differences in metabolite profiles between blood matrices, ages, and sexes among Caucasian individuals and their inter-individual variations

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  1. Article

    Open Access

    Plasma lipid profiling of different types of hepatic fibrosis induced by carbon tetrachloride and lomustine in rats

    Plasma lipid profiling has emerged as a useful tool for understanding the pathophysiology of hepatic injury and disease. Hepatic fibrosis results from chronic, progressive damage to the liver and can lead, in ...

    Masaki Ishikawa, Kosuke Saito, Hiroshi Yamada… in Lipids in Health and Disease (2016)

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  2. Article

    Open Access

    Comparison of circulating lipid profiles between fasting humans and three animal species used in preclinical studies: mice, rats and rabbits

    Circulating lipid metabolites are associated with many physiological and biological processes in the body, and therefore could be used as biomarkers for evaluating drug efficacy and safety in preclinical studi...

    Masaki Ishikawa, Kosuke Saito, Masayo Urata, Yuji Kumagai… in Lipids in Health and Disease (2015)

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  3. Article

    Open Access

    Lipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease

    Alzheimer’s disease (AD), the most common cause of dementia among neurodegenerative diseases, afflicts millions of elderly people worldwide. In addition to amyloid-beta (Aβ) peptide and phosphorylated tau, lip...

    Yoko Tajima, Masaki Ishikawa, Keiko Maekawa… in Lipids in Health and Disease (2013)

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