3 Result(s)
within
Keiko Maekawa
Life Sciences
Lipidology
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Article
Open AccessPlasma lipid profiling of different types of hepatic fibrosis induced by carbon tetrachloride and lomustine in rats
Plasma lipid profiling has emerged as a useful tool for understanding the pathophysiology of hepatic injury and disease. Hepatic fibrosis results from chronic, progressive damage to the liver and can lead, in ...
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Article
Open AccessComparison of circulating lipid profiles between fasting humans and three animal species used in preclinical studies: mice, rats and rabbits
Circulating lipid metabolites are associated with many physiological and biological processes in the body, and therefore could be used as biomarkers for evaluating drug efficacy and safety in preclinical studi...
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Article
Open AccessLipidomic analysis of brain tissues and plasma in a mouse model expressing mutated human amyloid precursor protein/tau for Alzheimer’s disease
Alzheimer’s disease (AD), the most common cause of dementia among neurodegenerative diseases, afflicts millions of elderly people worldwide. In addition to amyloid-beta (Aβ) peptide and phosphorylated tau, lip...
