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Open AccessUsing protein microarray technology to screen anti-ERCC1 monoclonal antibodies for specificity and applications in pathology
An antibody with cross-reactivity can create unexpected side effects or false diagnostic reports if used for clinical purposes. ERCC1 is being explored as a predictive diagnostic biomarker for cisplatin-based ...
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Article
Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity
As a critical apoptosis executioner, caspase-3 becomes activated and then enters into the nucleus to exert its function. However, the molecular mechanism of this nuclear entry of active caspase-3 is still unkn...
