3 Result(s)
within
Kazutaka Ikeda
Human Genetics
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Article
Open AccessTsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that is associated with neurological symptoms, including autism spectrum disorder. Tuberous sclerosis complex is caused by pathogenic germline...
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Article
Open AccessBrain hyperserotonemia causes autism-relevant social deficits in mice
Hyperserotonemia in the brain is suspected to be an endophenotype of autism spectrum disorder (ASD). Reducing serotonin levels in the brain through modulation of serotonin transporter function may improve ASD ...
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Article
Multi-phenotype behavioral characterization of inbred strains derived from wild stocks of Mus musculus
Many aspects of mouse behavior have been studied by using only a relatively small sample of available laboratory strains. These laboratory mice were derived from the so-called ``fancy mouse'' and in most case...
