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  1. No Access

    Article

    The effects of ipragliflozin on the liver-to-spleen attenuation ratio as assessed by computed tomography and on alanine transaminase levels in Japanese patients with type 2 diabetes mellitus

    We assessed the effects of a 12-week ipragliflozin treatment on the liver-to-spleen attenuation ratio (L/S ratio) using computed tomography and on alanine transaminase (ALT) levels in Japanese patients with type ...

    Yukihiro Bando, Ayumi Ogawa, Kazuhide Ishikura, Hideo Kanehara… in Diabetology International (2017)

  2. Article

    Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells

    Impaired angiogenesis induced by vascular endothelial growth factor (VEGF) resistance is a hallmark of vascular complications in type 2 diabetes; however, its molecular mechanism is not fully understood. We ha...

    Kazuhide Ishikura, Hirofumi Misu, Masafumi Kumazaki, Hiroaki Takayama… in Diabetologia (2014)

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    Article

    Determinants of the HbA1c-lowering effect of sitagliptin when added to ongoing insulin therapy in Japanese patients with type 2 diabetes

    This study assessed the independent predictors of the HbA1c-lowering effect of sitagliptin when added to ongoing insulin therapy in Japanese patients with type 2 diabetes.

    Yukihiro Bando, Kazuhide Ishikura, Hideo Kanehara, Keiko Aoki… in Diabetology International (2013)