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Reference Work Entry In depth
Sphingomyelinase, Acidic
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Living Reference Work Entry In depth
Sphingomyelinase, Acidic
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Chapter
Acid Sphingomyelinase
The enzyme acid sphingomyelinase catalyzes the hydrolysis of sphingomyelin to ceramide. The importance of the enzyme for cell functions was first recognized in Niemann–Pick disease type A and B, the genetic di...