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  1. Article

    Open Access

    Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers

    Homologous recombination (HR) deficiency is associated with DNA rearrangements and cytogenetic aberrations1. Paradoxically, the types of DNA rearrangements that are specifically associated with HR-deficient cance...

    Jeremy Setton, Kevin Hadi, Zi-Ning Choo, Katherine S. Kuchin, Huasong Tian in Nature (2023)