10 Result(s)
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Katherine A. Sauder
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Article
Open AccessUsing Power Analysis to Choose the Unit of Randomization, Outcome, and Approach for Subgroup Analysis for a Multilevel Randomized Controlled Clinical Trial to Reduce Disparities in Cardiovascular Health
We give examples of three features in the design of randomized controlled clinical trials which can increase power and thus decrease sample size and costs. We consider an example multilevel trial with several ...
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Article
Reducing Maternal Obesity and Diabetes Risks Prior to Conception with the National Diabetes Prevention Program
Intrauterine exposure to maternal obesity and hyperglycemia greatly increases offspring health risks. Scalable lifestyle interventions to lower weight and glycemia prior to conception are needed, but have been...
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Open AccessPrenatal exposure to tobacco and adverse birth outcomes: effect modification by folate intake during pregnancy
Fetal exposure to tobacco increases the risk for many adverse birth outcomes, but whether diet mitigates these risks has yet to be explored. Here, we examined whether maternal folate intake (from foods and sup...
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Adherence to index-based dietary patterns in childhood and BMI trajectory during the transition to adolescence: the EPOCH study
In the United States, one in five adolescents are obese. Index-based dietary patterns are measures of the overall diet that have the potential to serve as valuable obesity risk stratification tools. However, l...
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How does exposure to overnutrition in utero lead to childhood adiposity? Testing the insulin hypersecretion hypothesis in the EPOCH cohort
Our aim was to explore metabolic pathways linking overnutrition in utero to development of adiposity in normal-weight children.
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Correction to: Maternal blood glucose level and offspring glucose–insulin homeostasis: what is the role of offspring adiposity?
A Correction to this paper has been published: https://doi.org/10.1007/s00125-021-05432-4
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Article
Reducing intergenerational obesity and diabetes risk
To address the intergenerational transmission of obesity and diabetes, strategies promoting the health of women of reproductive age appear to be urgently needed. In this narrative review, we summarise what has...
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Maternal blood glucose level and offspring glucose–insulin homeostasis: what is the role of offspring adiposity?
The aim of this work was to investigate the association of maternal HbA1c during mid-pregnancy with biomarkers of glucose–insulin homeostasis during early childhood (4–7 years of age) and to assess whether and ho...
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Persistent effects of in utero overnutrition on offspring adiposity: the Exploring Perinatal Outcomes among Children (EPOCH) study
We previously showed that intrauterine exposure to gestational diabetes mellitus (GDM) increases selected markers of adiposity in pre-pubertal adolescents. In the present study, we examined these associations ...
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Article
Open AccessEffects of culinary spices and psychological stress on postprandial lipemia and lipase activity: results of a randomized crossover study and in vitro experiments
Data suggest that culinary spices are a potent, low-calorie modality for improving physiological responses to high fat meals. In a pilot study (N = 6 healthy adults), we showed that a meal containing a high an...
