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Open AccessCardiovascular autonomic regulation correlates with cognitive performance in patients with a history of traumatic brain injury
Traumatic brain injury (TBI) may afflict brain areas contributing to both cardiovascular autonomic regulation and cognitive performance. To evaluate possible associations between both functions in patients wit...
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Article
Open AccessAbsenteeism and associated labour costs according to depressive symptom severity in the German general population: why preventive strategies matter
Depression is a highly prevalent mental health condition with substantial individual, societal and economic consequences. This study focussed on the association of depressive symptom severity with absenteeism ...
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Cognitive Disorders
Cognitive disorders (CD), including delirium, minor cognitive disorder, and major cognitive disorder (dementia), often have an adverse impact on sexuality. Cognitive disorders may interfere with sexual functio...
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Article
Subtype-selective GABAA receptor mimetics—novel antihyperalgesic agents?
Agonists at the benzodiazepine-binding site of ionotropic γ-aminobutyric acid (GABAA) receptors are in clinical use as hypnotics, anxiolytics, and anticonvulsants since the early 1960. Analgesic effects of classi...
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Article
Reversal of pathological pain through specific spinal GABAA receptor subtypes
The chronic pain that accompanies inflammatory disease and nerve injury is often resistant to conventional analgesics, hence the interest in establishing the mechanisms that induce this pain. Growing evidence ...