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Article
Open AccessConditional survival to assess prognosis in patients with chronic lymphocytic leukemia
Biomarkers in chronic lymphocytic leukemia (CLL) allow assessment of prognosis. However, the validity of current prognostic biomarkers based on a single assessment point remains unclear for patients who have s...
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Article
Open AccessA systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites
Although vasculo-protective effects of flavan-3-ols are widely accepted today, their impact on endothelial cell functions and molecular mechanisms of action involved is not completely understood. The aim of th...
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Article
Open AccessGLI2 promoter hypermethylation in saliva of children with a respiratory allergy
The prevalence of respiratory allergy in children is increasing. Epigenetic DNA methylation changes are plausible underlying molecular mechanisms.
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Article
Open AccessIdentification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease
Genome-wide Illumina InfiniumMethylation 450 K DNA methylation analysis was performed on blood samples from clinical atherosclerosis patients (n = 8) and healthy donors (n = 8) in the LVAD study (NCT02174133, ...
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Article
Open AccessFrom inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
The progressively older population in developed countries is reflected in an increase in the number of people suffering from age-related chronic inflammatory diseases such as metabolic syndrome, diabetes, hear...