3 Result(s)
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Katarzyna Kent
English
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Article
Open AccessMolecular dissection and testing of PRSS37 function through LC–MS/MS and the generation of a PRSS37 humanized mouse model
The quest for a non-hormonal male contraceptive pill for men still exists. Serine protease 37 (PRSS37) is a sperm-specific protein that when ablated in mice renders them sterile. In this study we sought to exa...
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Article
Open AccessThe testis-specific E3 ubiquitin ligase RNF133 is required for fecundity in mice
Ubiquitination is a post-translational modification required for a number of physiological functions regulating protein homeostasis, such as protein degradation. The endoplasmic reticulum (ER) quality control ...
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Article
Open AccessLarge-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets
The development of a safe, effective, reversible, non-hormonal contraceptive method for men has been an ongoing effort for the past few decades. However, despite significant progress on elucidating the functio...
