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  1. Article

    Open Access

    The Effect of Food Intake on the Pharmacokinetics of Oral Basal Insulin: A Randomised Crossover Trial in Healthy Male Subjects

    Oral insulin 338 is a novel tablet formulation of a long-acting basal insulin. This randomised, open-label, four-period crossover trial investigated the effect of timing of food intake on the single-dose pharm...

    Inge B. Halberg, Karsten Lyby, Karsten Wassermann, Tim Heise… in Clinical Pharmacokinetics (2019)

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    Article

    Doxorubicin binds in a cooperative manner to myocardial cells

    Experimental evidence indicates that the anthracycline antibiotic doxorubicin (adriamycin) localizes mainly in cell nuclei of cardiac cells and has a high affinity to several cellular constituents in addition ...

    Karsten Wassermann, Eva Steiness in Cancer Chemotherapy and Pharmacology (1986)

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    Article

    Similar changes in cardiac morphology and DNA synthesis induced by doxorubicin and 4′-epi-doxorubicin

    Doxorubicin is an antineoplastic agent whose clinical administration is limited by dose-dependent irreversible cardiomyopathy. Doxorubicin inhibits the rate of DNA synthesis in cultured rat myocardial cells af...

    Karsten Wassermann, Kjeld Mølgaard, Eva Steiness in Cancer Chemotherapy and Pharmacology (1985)