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  1. No Access

    Article

    Expression of interferon regulatory factors and indoleamine 2,3-dioxygenase in Chlamydia trachomatis-infected synovial fibroblasts

    Synovial fibroblasts probably represent host cells for Chlamydia trachomatis during initial intra-articular infection in reactive arthritis. In vitro synovial cells produce interferon-β (IFN-β) in response to ch...

    J. Rödel, Annemarie Groh, Matthias Hartmann… in Medical Microbiology and Immunology (1999)

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    Chapter

    Virulence of Streptococcus pyogenes for Chicken Embryos after Isogenic Inactivation of Different Streptococcal Pathogenicity Factors

    M protein of Streptococcus pyogenes has been postulated as the major virulence factor of group A streptococci (GAS) based on its association with a phagocytosis-resistant phenotype (4). The antiphagocytic propert...

    Karl-Hermann Schmidt, Andreas Podbielski, Werner Reichardt… in Streptococci and the Host (1997)

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    Chapter

    Group A Streptococcal M Protein Binds to Several Human Cell Types but not via MHC Class II Molecules

    M protein is known as the major virulence factor of group A streptococci. Only a few years ago, M protein has been reported to be a superantigen like the streptococcal erythrogenic toxins ETA and ETC (3). Supe...

    Barbara Wagner, Karl-Hermann Schmidt, Bernhard Fleischer… in Streptococci and the Host (1997)

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    Chapter

    Map** of Binding Sites for Human Serum Albumin and Fibrinogen on the M3-Protein

    The emm3-gene and the emm78-gene encoding the M-protein type 3 (OF-) resp. type 78 (OF+) of Streptococcus pyogenes were completely sequenced (AC-No.: X80168) and the recombinant proteins expressed in E. coli. Con...

    Werner Reichardt, Karl-Hermann Schmidt, Cornelia Amberg… in Streptococci and the Host (1997)

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    Article

    Expression of both M protein and hyaluronic acid capsule by group A streptococcal strains results in a high virulence for chicken embryos

    The human pathogenic microorganismStreptococcus pyogenes can resist against phagocytic attack of human granulocytes. Streptococcal M protein and hyaluronic acid were identified as virulence factors involved in th...

    Karl-Hermann Schmidt, Elisabeth Günther… in Medical Microbiology and Immunology (1996)

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    Article

    Superantigens and pseudosuperantigens of gram-positive cocci

    Superantigens use an elaborate and unique mechanism of T lymphocyte stimulation. Prototype superantigen are the pyrogenic exotoxins produced by Staphylococcus aureus and Streptococcus pyogenes. Many candidate pro...

    Bernhard Fleischer, Dieter Gerlach, Andreas Fuhrmann… in Medical Microbiology and Immunology (1995)