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Article
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
Greg Gibson and colleagues integrate summary-level GWAS and eQTL data with RNA-seq data from a cohort of pediatric Crohn's disease and report transcriptional risk scores that identify patients who will progres...
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Article
Genetic differences in Crohn's disease susceptibility and outcome
A new genome-wide association study (GWAS) has been conducted to discover genetic contributions that can explain disease prognosis in Crohn's disease. This understudied area deserves attention for discovering ...
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Article
Open AccessSeqAnt: A web service to rapidly identify and annotate DNA sequence variations
The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that identify tens of thousands to millions of...