-
Article
Vimentin promotes glioma progression and maintains glioma cell resistance to oxidative phosphorylation inhibition
Glioma has been demonstrated as one of the most malignant intracranial tumors and currently there is no effective treatment. Based on our previous RNA-sequencing data for oxidative phosphorylation (OXPHOS)-inh...
-
Article
Open AccessCaveolin-1 promotes glioma progression and maintains its mitochondrial inhibition resistance
Glioma is a lethal brain cancer and lacking effective therapies. Challenges include no effective therapeutic target, intra- and intertumoral heterogeneity, inadequate effective drugs, and an immunosuppressive ...
-
Article
Genome resource of Xanthomonas oryzae pv. oryzae Chinese strain NE-8 causing bacterial blight of rice
-
Article
Synthetic lethality in personalized cancer therapy
Genomic instability is one of the hallmarks of tumors that contributes to tumor heterogeneity and drug resistance. Genetically targeted cancer therapy that focused on genome instability has been a direction fo...
-
Chapter
Targeted Gene Replacement in Plants Using CRISPR-Cas Technology
The CRISPR-Cas based genome editing systems have been widely used in plant functional genomics research and crop improvement due to its simplicity, high efficiency and specificity. For example, the CRISPR-Cas9...
-
Chapter
Genome Editing Is Revolutionizing Crop Improvement
The ever-increasing human population together with emerging environmental cues from climate change demand for novel innovations in plant breeding and agriculture. Targeted genome editing technologies especiall...
-
Chapter
Genome Editing Toward Rice Improvement
Rice (Oryza sativa L.) serves as the major food source feeding half of the world’s population. In the past century, the pedigree-based conventional, radiation-based mutational and DNA marker-based molecular breed...
-
Chapter
Genome Editing and Rice Grain Quality
Rice grain yield has been long on the scope of scientists looking for a tool to develop new high yielding genotypes with high-quality traits. Grain quality is always driving the market of rice and its importan...
-
Article
Open AccessRNA-Seq analysis of gene expression changes triggered by Xanthomonas oryzae pv. oryzae in a susceptible rice genotype
Xanthomonas oryzae pv. oryzae (Xoo) is a destructive disease in most of the rice growing regions worldwide. Xoo injects the transcriptional activator-like (TAL) effector protein into the host cell to induce the s...
-
Article
Open AccessTranscriptome analysis of a rice cultivar reveals the differentially expressed genes in response to wild and mutant strains of Xanthomonas oryzae pv. oryzae
Bacterial blight (BB), caused by Xanthomonas oryzae pv. oryzae (Xoo), is a devastating disease in most of the rice growing regions worldwide. Among the 42 BB resistance (R) genes, Xa23 is an executor R gene, conf...
-
Article
Rht23 (5Dq′) likely encodes a Q homeologue with pleiotropic effects on plant height and spike compactness
The domesticated gene Q on wheat chromosome 5A (5AQ) encodes an AP2 transcription factor. The 5AQ was originated from a G to A mutation in exon 8 and/or C to T transition in exon 10 and resulted in free-threshing...
-
Article
Genome editing technologies and their applications in crop improvement
Crop improvement is very essential to meet the increasing global food demands and enhance food nutrition. Conventional crop-breeding methods have certain limitations such as taking lot of time and resources, a...
-
Article
Magnetic-Based Fano Resonance by a Trimer with Y-shaped Gap
We introduce a Y-shaped gap into a silver disk to break the structure symmetry which can be looked as a loop-linked structure. Magnetic resonances are excited by incident light when incident electric field is ...
-
Article
Manipulation of Magnetic Fano Resonances in Double Split-Hole Disk
The plasmon resonances and magnetic field enhancement in double split-hole disk are investigated by using finite element method. The multipolar modes and the magnetic Fano resonances of the double split-hole d...
-
Article
Manipulation of Electrical Field Enhancements and Fano Resonances in Nanoellipsoid/Ring Plasmonic Cavities
Surface plasmon resonances of an ellipsoid-ring nanostructure with spatial symmetry breaking have been investigated theoretically. In this plasmonic system, the multiple Fano resonances are enhanced and can be...
-
Article
High-resolution genetic map** of rice bacterial blight resistance gene Xa23
Bacterial blight (BB) caused by Xanthomonas oryzae pv. oryzae (Xoo) is the most devastating bacterial disease of rice (Oryza sativa L.), a staple food crop that feeds half of the world’s populatio...
