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  1. Article

    Open Access

    SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma

    Ewing sarcoma (ES), which is characterized by the presence of oncogenic fusion proteins such as EWS/FLI1, is an aggressive pediatric malignancy with a high rate of early dissemination and poor outcome after di...

    Connor J. Hughes, Kaiah M. Fields, Etienne P. Danis… in Nature Communications (2023)

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  2. Article

    Open Access

    Spatiotemporal control of necroptotic cell death and plasma membrane recruitment using engineered MLKL domains

    Necroptosis is a form of programmed necrotic cell death in which a signaling cascade induces oligomerization of mixed lineage kinase domain-like (MLKL) protein, leading to plasma membrane rupture. Necroptotic ...

    Amir Taslimi, Kaiah M. Fields, Kristin D. Dahl, Qi Liu… in Cell Death Discovery (2022)

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