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  1. Article

    Open Access

    Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis

    B-cell acute lymphoblastic leukemia (B-ALL) comprises over 85% of all acute lymphoblastic leukemia (ALL) cases and is the most common childhood malignancy. Although the 5 year overall survival of patients with...

    Lan Huang, **zhou An, Yao Zhu, Kainan Zhang, Li **ao… in Cell Communication and Signaling (2022)

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    Article

    A novel mutant PIK3R1EY451delinsD breast cancer patient resistant to HER2-targeted therapy treated with everolimus: a case report

    Resistance to HER2-targeted therapy is a critical issue in breast cancer that must be addressed immediately. PIK3R1 mutations are more common in Chinese breast cancer patients (17%, 25/147, Fudan University Sh...

    Kainan Wang, Ye Hu, Lingzhi Xu, Shanshan Zhao, Chen Song… in Molecular Biology Reports (2022)