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  1. Article

    Open Access

    Validating the role of PTGIS gene in colorectal cancer by bioinformatics analysis and in vitro experiments

    Prostaglandin I2 synthase (PTGIS) is a member of the cytochrome P450 family. Studies have revealed that differential expression of the PTGIS gene is closely related to the pathological and physiological proces...

    Hui Ding, Kai-yun Wang, Si-yang Chen, Kai-Wen Guo, Wen-hong Qiu in Scientific Reports (2023)

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  2. No Access

    Article

    Cornel Iridoid Glycoside Regulates Modification of Tau and Alleviates Synaptic Abnormalities in Aged P301S Mice

    Alzheimer’s disease (AD), also defined as a tauopathology, is a common neurodegenerative disease. Hyper-phosphorylation, cleavage or truncation, and aggregation of tau contribute to AD. Thus, targeting the pos...

    Cui-cui Yang, Yi Luo, Kai-wen Guo, Ceng-ceng Zheng, Lin Li… in Current Medical Science (2020)

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    Article

    Essential Oil from Carpesium abrotanoides L. Induces Apoptosis via Activating Mitochondrial Pathway in Hepatocellular Carcinoma Cells

    The effects of essential oil from Carpesium abrotanoides L. (CAEO) on the proliferation and apoptosis of human hepatic cancer cells were investigated in this study. MTT assays indicated that CAEO inhibited the pr...

    Qiang Wang, Li-hong Pan, Li Lin, Ren Zhang, Yu-chao Du, Hao Chen… in Current Medical Science (2018)