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  1. No Access

    Article

    The pleiotropic benefits of statins include the ability to reduce CD47 and amplify the effect of pro-efferocytic therapies in atherosclerosis

    The pleiotropic benefits of statins may result from their impact on vascular inflammation. The molecular process underlying this phenomenon is not fully elucidated. In the present study, RNA-sequencing designe...

    Kai-Uwe Jarr, Jianqin Ye, Yoko Kojima, Zhongde Ye… in Nature Cardiovascular Research (2022)

  2. No Access

    Article

    Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis

    Atherosclerosis is the process that underlies heart attack and stroke. A characteristic feature of the atherosclerotic plaque is the accumulation of apoptotic cells in the necrotic core. Prophagocytic antibody...

    Alyssa M. Flores, Niloufar Hosseini-Nassab, Kai-Uwe Jarr… in Nature Nanotechnology (2020)