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  1. Article

    Open Access

    A genetic algorithm-based boolean delay model of intracellular signal transduction in inflammation

    Signal transduction is the major mechanism through which cells transmit external stimuli to evoke intracellular biochemical responses. Understanding relationship between external stimuli and corresponding cell...

    Chu Chun Kang, Yung Jen Chuang, Kai Che Tung, Chun Cheih Chao in BMC Bioinformatics (2011)

  2. Article

    Open Access

    Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-κB signaling-induced gene expression responses in inflammation

    Signal transduction is the major mechanism through which cells transmit external stimuli to evoke intracellular biochemical responses. Diverse cellular stimuli create a wide variety of transcription factor act...

    Shih Chi Peng, David Shan Hill Wong, Kai Che Tung, Yan Yu Chen in BMC Bioinformatics (2010)