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Article
Loss of heterozygosity on chromosome 18q is associated with muscle-invasive transitional cell carcinoma of the bladder
Somatic allelic loss is regarded as a hallmark of tumour-suppressor gene (TSG) inactivation. Thirty-one human bladder transitional cell carcinomas (TCCs) were examined for allelic loss at five chromosome 18q l...
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Article
Loss of chromosome 11p alleles in cultured cells derived from Wilms' tumours
Cell cultures have been produced from five Wilms' tumours. All cultures had a finite lifespan and a pattern of antigen expression which indicated that the cells were derived from the differentiated components ...
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Article
Malignant progression of an SV40-transformed human epidermal keratinocyte cell line
Human foetal keratinocytes were transfected with a recombinant plasmid (pSV6-1) which contained an origin defective SV40 genome. The resulting transformed cell line had many properties in common with previousl...
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Article
Sulphation and fibronectin-binding properties of heparan sulphate glycosaminoglycans from transformed cultured human keratinocytes