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Article
Open AccessDrone versus ambulance for blood products transportation: an economic evaluation study
Medical transportation is an essential step in health care services, and includes ground, air and water transportation. Among the important uses of medical transportation is the delivery of blood products in t...
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Article
Open AccessTip** the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death
Induction of tumor cell death is the therapeutic goal for most anticancer drugs. Yet, a mode of drug-induced cell death, known as immunogenic cell death (ICD), can propagate antitumoral immunity to augment the...
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Article
MicroROM: A Physics-Based Constitutive Model for Ni-Based Superalloys
In this article, a physics-based constitutive model is developed for representing the stress–plastic strain response of Ni-based superalloys by considering the hardening mechanisms that contribute to the macro...
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Article
Open AccessSpin-transfer torque generated in graphene based topological insulator heterostructures
We studied the spin-transfer torque (STT) in graphene based normal-metal/topological-insulator/ferromagnet heterostructures (N/TI/F), which is induced by the helical spin-polarized current in the quantum spin ...
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Article
Fatigue Crack Prognostics by Optical Quantification of Defect Frequency
Defect frequency, a fatigue crack prognostics indicator, is defined as the number of microcracks per second detected using a laser beam that is scanned across a surface at a constant predetermined frequency. I...
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Open AccessESICM LIVES 2016: part two
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Open AccessESICM LIVES 2016: part one
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Article
Open AccessElectrically controllable sudden reversals in spin and valley polarization in silicene
We study the spin and valley dependent transport in a silicene superlattice under the influence of a magnetic exchange field, a perpendicular electric field and a voltage potential. It is found that a gate-vol...
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Article
Has Choosing Wisely® affected rates of dual-energy X-ray absorptiometry use?
Reducing overuse of tests such as dual-energy X-ray absorptiometry (DXA) scans in younger women is an important quality issue. We evaluated trends in DXA ordering before and after Choosing Wisely recommendatio...
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Article
Depression symptoms across cultures: an IRT analysis of standard depression symptoms using data from eight countries
Prevalence estimates of depression vary between countries, possibly due to differential functioning of items between settings. This study compared the performance of the widely used Hopkins symptom checklist 1...
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Article
Open AccessAssociation of endothelin-1 and matrix metallopeptidase-9 with metabolic syndrome in middle-aged and older adults
Metabolic syndrome (MetS) contains a cluster of cardiovascular risk factors. People with MetS are more susceptible to cardiovascular disease, diabetes mellitus, and cancer. Endothelin-1 (ET-1) and matrix metal...
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Article
Open AccessAssessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients
Recent discoveries in cancer research have revealed a plethora of clinically actionable mutations that provide therapeutic, prognostic and predictive benefit to patients. The feasibility of screening mutations...
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Article
In-Situ SEM J-Testing and Crack-Tip Micromechanics of Zircaloy-4 by Three-Point Bending
A three-point bend fixture has been designed, fabricated, and utilized to demonstrate the feasibility of performing in-situ J-testing at ambient and elevated temperatures inside a scanning electron microscope (SE...
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Article
Open AccessMitosis-targeted anti-cancer therapies: where they stand
The strategy of clinically targeting cancerous cells at their most vulnerable state during mitosis has instigated numerous studies into the mitotic cell death (MCD) pathway. As the hallmark of cancer revolves ...
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Article
Open AccessSurvivin withdrawal by nuclear export failure as a physiological switch to commit cells to apoptosis
Apoptosis is a tightly controlled process regulated by many signaling pathways; however, the mechanisms and cellular events that decide whether a cell lives or dies remain poorly understood. Here we showed tha...
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Article
Fracture toughness of zirconia nanoparticle-filled dental composites
The fracture toughness of dental composites containing zirconia nanoparticles dispersed in a bisphenol A glycol dimethacrylate-based monomer blend (GTE) was studied for several yttria contents. Three-point ben...
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Article
Evolution of Slip Morphology and Fatigue Crack Initiation in Surface Grains of Ni200
The evolution of slipbands into fatigue cracks in surface grains of commercially pure Ni, Ni200 (99.35Ni-0.4Fe-0.25Cu, in wt pct), was studied at ambient temperature. Round-bar specimens with electropolished s...
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Article
In-Situ Fracture Studies and Modeling of the Toughening Mechanism Present in Wrought Low-Carbon Arc-Cast Molybdenum, Titanium-Zirconium-Molybdenum, and Oxide-Dispersion-Strengthened Molybdenum Flat Products
In-situ testing, ultrasonic C-scans, and metallography were used to show that a crack-divider delamination form of thin-sheet toughening occurs in wrought low-carbon arc-cast (LCAC) unall...
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Article
Effects of Deformation-Induced Constraint on High-Cycle Fatigue in Ti Alloys with a Duplex Microstructure
The effects of the deformation behaviors of individual phases in Ti alloys with a duplex microstructure containing a mixture of primary α grains and lamellar α + β colonies have been analyzed by applying the fini...
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Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis
Recently, our laboratory demonstrated that Stat3 is required for the de novo development of chemically-induced skin tumors. We have further investigated the role of Stat3 in epithelial carcinogenesis using mice i...
