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Open AccessRobustness of large-area suspended graphene under interaction with intense laser
Graphene is known as an atomically thin, transparent, highly electrically and thermally conductive, light-weight, and the strongest 2D material. We investigate disruptive application of graphene as a target of...
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Article
Blood glucose target in acute phase suggested by the analysis of the relationship between blood glucose profile and the severity of the diseases
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Article
Open AccessRole of multifunctional transcription factor TFII-I and putative tumour suppressor DBC1 in cell cycle and DNA double strand damage repair
In multicellular organisms, precise control of cell cycle and the maintenance of genomic stability are crucial to prevent chromosomal alterations. The accurate function of the DNA damage pathway is maintained ...
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Open AccessVariable and maximum blood glucose levels during the first week after ICU admission are related to the severity of the patients
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Article
Open AccessMultifunctional transcription factor TFII-I is an activator of BRCA1 function
The TFII-I is a multifunctional transcriptional factor known to bind specifically to several DNA sequence elements and to mediate growth factor signalling. A microdeletion at the chromosomal location 7q11.23 e...
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Open AccessInvestigation of the blood glucose target for mortality reduction by means of bedside-type artificial pancreas
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CIP-Based Numerical Simulation of Snow Avalanche
In order to predict a flow area of snow avalanche, a numerical method based on fluid dynamics has been proposed. In the CIP-based numerical method, snow is modeled as a Bingham fluid with the consideration of ...
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Article
Genome-wide single-nucleotide polymorphism arrays in endometrial carcinomas associate extensive chromosomal instability with poor prognosis and unveil frequent chromosomal imbalances involved in the PI3-kinase pathway
Endometrial cancer is one of the tumor types in which either chromosomal instability (CIN) or microsatellite instability (MSI) may occur. It is known to possess mutations frequently in the Ras-PI3K (phosphatid...
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Article
Open AccessIdentification of DBC1 as a transcriptional repressor for BRCA1
DBC1/KIAA1967 (deleted in breast cancer 1) is a putative tumour-suppressor gene cloned from a heterozygously deleted region in breast cancer specimens. Caspase-dependent processing of DBC1 promotes apoptosis, and...
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Open AccessReply: Somatic mutations are present in all members of the AKT family in endometrial carcinoma
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Development and evaluation of a loop-mediated isothermal amplification method for the rapid detection of Chlamydophila pneumoniae
We developed a loop-mediated isothermal amplification (LAMP) method to detect Chlamydophila pneumoniae infection. This assay exclusively amplified C. pneumoniae sequences and no cross-reactivity was observed for ...
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Article
Open AccessThe oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas
The phosphatidylinositol 3′-kinase (PI3K)–AKT pathway is activated in many human cancers and plays a key role in cell proliferation and survival. A mutation (E17K) in the pleckstrin homology domain of the AKT1 re...
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Article
Groundwater contamination with arsenic in Sherajdikhan, Bangladesh: geochemical and hydrological implications
An integrated study has been carried out to elucidate the distribution and occurrence of arsenic in selected groundwater samples in the area of Sherajdikhan, Bangladesh. Arsenic and other parameters (T, pH, EC...
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Article
Fasciitis and myositis: an analysis of muscle-related complications caused by chronic GVHD after allo-SCT
The muscle-related complications of fasciitis and myositis, caused by chronic GVHD after Allo-SCT are relatively rare, but at times will severely impair a patient's quality of life (QOL). We performed a retros...
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Article
Behaviors of chemical elements in the atmosphere, Kawasaki, Japan
A total of 19 elements in the samples of atmospheric deposition collected in Kawasaki, Japan, were determined by neutron activation analysis, ICPAES and flame photometry. The amounts of soil dust depositions w...
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Article
New Classification of Cystic Duct Carcinoma
Farrar’s criteria for cystic duct carcinoma (histopathologic diagnosis of a carcinoma strictly limited to the cystic duct) are impractical especially when making a diagnosis of primary cystic duct carcinoma in...
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Molecular remission of multiple myeloma with cytoreductive autografting followed by a dose-reduced allograft
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Successful engraftment by second cord blood transplantation with reduced-intensity conditioning after graft rejection due to hemophagocytic syndrome following initial CBT
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Successful matched unrelated BMT for secondary AML which developed simultaneously with relapsed Hodgkin's lymphoma
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Open AccessSlug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
Slug, a member of the Snail family of transcription factors, plays a crucial role in the regulation of epithelial-mesenchymal transition (EMT) by suppressing several epithelial markers and adhesion molecules i...
