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  1. Article

    The tumour necrosis factor alpha –238 G → A and –308 G → A promoter polymorphisms are not associated with insulin sensitivity and insulin secretion in young healthy relatives of Type II Diabetic patients

    Aims/hypothesis. Tumour necrosis factor-α (TNF-α) is believed to influence skeletal muscle insulin resistance. Two G → A transitions in the promoter region of TNF- α at position –...

    M. Koch, K. Rett, A. Volk, E. Maerker, K. Haist, M. Weisser, A. Rettig in Diabetologia (2000)

  2. Article

    35th Annual Meeting of the European Association for the Study of Diabetes

    A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang in Diabetologia (1999)

  3. Article

    The PPARγ2 amino acid polymorphism Pro 12 Ala is prevalent in offspring of Type II diabetic patients and is associated to increased insulin sensitivity in a subgroup of obese subjects

    Aims/hypothesis. Recently a mutation in the coding sequence of the adipocyte specific isoform peroxisome proliferator-activated receptor γ2 (PPARγ2) was described, leading to the substitution of ...

    M. Koch, K. Rett, E. Maerker, A. Volk, K. Haist, M. Deninger, W. Renn in Diabetologia (1999)