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  1. No Access

    Article

    Prevalence of obesity was related to HLA-DQ in 2–4-year-old children at genetic risk for type 1 diabetes

    Body size is postulated to modulate type 1 diabetes as either a trigger of islet autoimmunity or an accelerator to clinical onset after seroconversion. As overweight and obesity continue to rise among children...

    J Yang, Å Lernmark, U M Uusitalo, K F Lynch, R Veijola… in International Journal of Obesity (2014)

  2. Article

    GAD65 vaccination: 5 years of follow-up in a randomised dose-escalating study in adult-onset autoimmune diabetes

    The aim of this study was to ascertain whether treatment of GAD65 autoantibody (GADA)-positive diabetic patients with alum-formulated recombinant GAD65 (GAD-alum) is safe and does not compromise beta cell func...

    C.-D. Agardh, K. F. Lynch, M. Palmér, K. Link, Å. Lernmark in Diabetologia (2009)

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  3. Article

    The type 1 diabetes protective HLA DQB1*0602 allele is less frequent in gestational diabetes mellitus

    We tested whether gestational diabetes mellitus (GDM) is associated with HLA-DQ genotypes.

    A. Papadopoulou, K. F. Lynch, N. Shaat, A. Nilsson, B. Lernmark… in Diabetologia (2009)

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  4. No Access

    Article

    Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype

    Human leukocyte antigen DQ (HLA-DQ) genetic factors and islet autoantibodies are strongly associated with type 1 diabetes (T1D) and are currently used to predict T1D. This study examined whether islet autoanti...

    K F Lynch, B Lernmark, J Merlo, C M Cilio, S-A Ivarsson… in Journal of Perinatology (2008)