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  1. No Access

    Chapter and Conference Paper

    Origin of Peptides Presented by MHC Class I Molecules: Generation by Proteasomes Precedes Evolution of the Immune System

    Major histocompatibility complex (MHC) class I molecules present peptide epitopes, derived from cytosolic and nuclear proteins, for recognition by CD8+ T cells. The vast majority of these epitopes are derived fro...

    G. Niedermann, K. Eichmann in Symposium in Immunology VII (1998)

  2. No Access

    Chapter and Conference Paper

    Cell Interaction Molecules Regulating T Cell Receptor Mediated Signal Transduction: A Comparison of Peripheral T Cell with Develo** Thymocytes

    Signal transduction through the αβ CD3 T cell receptor (TCR) can induce vastly different cellular responses at different stages of T cell differentiation. The earliest form of TCR mediated signalling is seen i...

    K. Eichmann, T. Bartlott, A. Ehrfeld, C. Levelt… in Progress in Immunology Vol. VIII (1993)

  3. No Access

    Book and Conference Proceedings

    Progress in Immunology

    Vol. VII: Proceedings of the 7th International Congress Immunology Berlin 1989

    Fritz Melchers, E. D. Albert, H. von Boehmer… (1989)

  4. No Access

    Chapter and Conference Paper

    Somatic Variation of Antigen-Recognition Specificity in H-2b-TNP-Specific Cytotoxic T-Cell Clones

    The molecular mechanisms involved in MHC-restricted antigen recognition by T cells are incompletely understood. For example, the strikingly precise ability of certain T-cell clones to distinguish very similar ...

    H. U. Weltzien, K. Eichmann in Specificity and Function of Clonally Develo** T Cells (1986)

  5. No Access

    Chapter

    Isotype Restriction of Idiotopes found on Human Anti-Carbohydrate Antibodies

    Sharing of idiotopes between IgM and IgG antibodies has been taken as evidence for the integrity of V gene products transferred during isotype switching from μ to γ heavy chains.

    F. Emmrich, G. Zenke, K. Eichmann in The Molecular Basis of B-Cell Differentiat… (1986)

  6. No Access

    Article

    Aged murine killer T-cell clones acquire specific cytotoxicity for P815 mastocytoma cells

    T-cell clones that grow continuously in tissue culture have become a major tool for studying the properties of T lymphocytes. It is therefore important to know to what extent such clones resemble their normal ...

    M. M. Simon, H. U. Weltzien, H. J. Bühring, K. Eichmann in Nature (1984)

  7. No Access

    Chapter

    Quantitative Estimates of Diversity, Degeneracy, and Connectivity in an Idiotypic Network among T Cells

    We have previously described a series of limiting dilution experiments in which several T-cell types of a number of different antigenic specificties were analyzed(1–5) In these studies, we obtained data on the pr...

    K. Fey, M. M. Simon, I. Melchers, K. Eichmann in The Biology of Idiotypes (1984)

  8. No Access

    Article

    Network regulation among T cells; Conclusions from limiting dilution experiments

    K. Eichmann, K. Fey, R. Kuppers, I. Melchers… in Springer Seminars in Immunopathology (1983)

  9. No Access

    Chapter and Conference Paper

    The Network Concept and Leukemia

    Network regulation undoubtedly represents a major mechanism for the maintenance of steady states in the immune system. This is brought out by a large body of experimental evidence suggesting that every antigen...

    K. Eichmann in Modern Trends in Human Leukemia IV (1981)

  10. No Access

    Article

    Conclusion: A simple, conservative model for antigen-specificity and MHC-restriction in lymphocyte communication

    K. Eichmann in Springer Seminars in Immunopathology (1980)

  11. No Access

    Article

    Communication between lymphocytes

    K. Eichmann in Springer Seminars in Immunopathology (1980)

  12. Article

    A cross-over chromosome combiningIg heavy chain genes of two mouse strains

    Two congenic strains of mice were bred in Konstanz that bear theIg heavy chain allotype gene of the C57BL/6 (Ig-1 b ) in a BALB/c background genome. One line (CB-8K) underwent e...

    Cornelia Kolb, E. Weiler, I. Seppälä, K. Eichmann, M. Kaartinen… in Immunogenetics (1979)

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  13. No Access

    Chapter and Conference Paper

    Genetic Control of T and B Cell Receptor Specificity in the Mouse

    The function of the immune system is based on a large variety of receptor molecules whose combining sites can recognize virtually every antigenic substance in the universe. This capacity is reflected in a pron...

    K. Eichmann, C. Berek, G. Hämmerling, S. Black, K. Rajewsky in The Immune System (1976)

  14. No Access

    Article

    Immunologische Analyse der Beziehungen zwischen den drei verschiedenen Typen von Antigendeterminanten normaler menschlicher Haptoglobine

    K. Eichmann, H. Deicher, H. Cleve in Humangenetik (1966)