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Article
Open AccessTranscriptomic landscape of TIMP3 oncosuppressor activity in thyroid carcinoma
Papillary thyroid cancer (PTC) is the most frequent thyroid tumor. The tissue inhibitor of metalloproteinase-3 (TIMP3) gene encodes a matrix metalloproteinases inhibitor that exerts a tumor suppressor role in ...
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Article
Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo
Galectin-1 (Gal-1) is involved in tumoral angiogenesis, hypoxia and metastases. Actually the Gal-1 expression profile in multiple myeloma (MM) patients and its pathophysiological role in MM-induced angiogenesi...
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Article
A progression-risk score to predict treatment-free survival for early stage chronic lymphocytic leukemia patients
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Article
Lenalidomide and low-dose dexamethasone for newly diagnosed primary plasma cell leukemia
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Article
Open AccessThe expression pattern of small nucleolar and small Cajal body-specific RNAs characterizes distinct molecular subtypes of multiple myeloma
Small nucleolar RNAs (snoRNAs) and small Cajal body-specific RNAs (scaRNAs) are non-coding RNAs involved in the maturation of other RNA molecules and generally located in the introns of host genes. It is now e...
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Article
HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients
The deregulation of the homeobox genes as homeoboxB (HOXB)-7 has been previously associated to tumor progression and angiogenesis; here we investigated the potential role of HOXB7 in the pro-angiogenic properties...
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Article
Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells
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Article
Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients
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Article
Transcriptional features of multiple myeloma patients with chromosome 1q gain