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Article
Clinical characteristics of women with familial pelvic floor disorders
Understanding the clustering of pelvic floor disorders (PFDs) within families is important because it may suggest underlying risk factors that may be environmental, genetic or both. The objective of this study...
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Article
Genome-wide linkage in Utah autism pedigrees
Genetic studies of autism over the past decade suggest a complex landscape of multiple genes. In the face of this heterogeneity, studies that include large extended pedigrees may offer valuable insights, as th...
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Article
A high-density SNP genome-wide linkage scan in a large autism extended pedigree
We performed a high-density, single nucleotide polymorphism (SNP), genome-wide scan on a six-generation pedigree from Utah with seven affected males, diagnosed with autism spectrum disorder. Using a two-stage ...