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  1. No Access

    Article

    Pyrazine Derivatives—Versatile Scaffold

    Pyrazines are important class of pharmacophores because of their versatility in pharmacological activity. Pyrazines are among the most widely known heterocyclic compounds those can be isolated from natural sou...

    N. Tambat, S. K. Mulani, A. Ahmad, S. B. Shaikh… in Russian Journal of Bioorganic Chemistry (2022)

  2. Article

    Open Access

    Experimental Validation of an ITAP Numerical Model and the Effect of Implant Stem Stiffness on Bone Strain Energy

    The Intraosseous Transcutaneous Amputation Prosthesis (ITAP) offers transfemoral amputees an ambulatory method potentially reducing soft tissue complications seen with socket and stump devices. This study vali...

    K. Ahmed, R. J. Greene, W. Aston, T. Briggs… in Annals of Biomedical Engineering (2020)

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    Article

    Treatment of cultured human astrocytes and vascular endothelial cells with protein kinase CK2 inhibitors induces early changes in cell shape and cytoskeleton

    Ubiquitous protein kinase CK2 is a key regulator of cell migration, proliferation and tumor growth. CK2 is abundant in retinal astrocytes, and its inhibition suppresses retinal neovascularization in a mouse re...

    A. A. Kramerov, A. G. Golub, V. G. Bdzhola… in Molecular and Cellular Biochemistry (2011)

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    Article

    Protein Kinase CK2 in Health and Disease

    Elevated levels of protein kinase CK2 (formerly casein kinase 2 or II) have long been associated with increased cell growth and proliferation both in normal and cancer cells. The ability of CK2 to also act as ...

    J. H. Trembley, G. Wang, G. Unger, J. Slaton… in Cellular and Molecular Life Sciences (2009)

  5. No Access

    Article

    Consequences of CK2 signaling to the nuclear matrix

    Protein kinase CK2 is recognized as one of the key cellular signals for cell growth and proliferation. Its nuclear targeting appears to be critical to its role in these functions. In the nucleus, nuclear matri...

    Shihui Yu, Huamin Wang, Alan Davis, K. Ahmed in Molecular and Cellular Biochemistry (2001)

  6. No Access

    Article

    Circadian variation of serum testosterone in the adult male rat with a late morning acrophase

    Serum testosterone concentrations were measured in adult male Sprague-Dawley rats. A significant circadian testosterone rhythm (p<0.01) was found with peak values at 10.00 and 13.00 h.

    M. J. Wilson, Dr. J. M. McMillin, U. S. Seal, K. Ahmed in Experientia (1976)