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    Article

    PTBP1 as a potential regulator of disease

    Polypyrimidine tract-binding protein 1 (PTBP1) is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, which plays a key role in alternative splicing of precursor mRNA and RNA metabolism. PT...

    Qi Yu, Tongtong Wu, Wenhong Xu, Junyuan Wei in Molecular and Cellular Biochemistry (2023)

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    Metabolic crosstalk in the tumor microenvironment regulates antitumor immunosuppression and immunotherapy resisitance

    The successful treatment of human cancers by immunotherapy has been made possible by breakthroughs in the discovery of immune checkpoint regulators, including CTLA-4 and PD-1/PD-L1. However, the immunosuppress...

    Fang Wei, Dan Wang, Junyuan Wei, Niwen Tang in Cellular and Molecular Life Sciences (2021)