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Article
Open AccessMonitoring Activity and Gait in Children (MAGIC) using digital health technologies
Digital health technologies (DHTs) can collect gait and physical activity in adults, but limited studies have validated these in children. This study compared gait and physical activity metrics collected using...
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Article
Open AccessDecentralized clinical trials and rare diseases: a Drug Information Association Innovative Design Scientific Working Group (DIA-IDSWG) perspective
Traditional clinical trials require tests and procedures that are administered in centralized clinical research sites, which are beyond the standard of care that patients receive for their rare and chronic dis...
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Article
Open AccessDemographic characteristics associated with circadian rest-activity rhythm patterns: a cross-sectional study
Rest-activity rhythm (RAR), a manifestation of circadian rhythms, has been associated with morbidity and mortality risk. However, RAR patterns in the general population and specifically the role of demographic...
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Article
Open AccessDevelopment of digital measures for nighttime scratch and sleep using wrist-worn wearable devices
Patients with atopic dermatitis experience increased nocturnal pruritus which leads to scratching and sleep disturbances that significantly contribute to poor quality of life. Objective measurements of nightti...
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Article
Organizing and Analyzing the Activity Data in NHANES
The NHANES study contains objectively measured physical activity data collected using hip-worn accelerometers from multiple cohorts. However, using the accelerometry data has proven daunting because (1) curren...
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Article
Joint and Individual Representation of Domains of Physical Activity, Sleep, and Circadian Rhythmicity
Developments in wearable technology have enabled researchers to continuously and objectively monitor various aspects and physiological domains of real life including levels of physical activity, quality of sle...
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Article
Open AccessNovel metrics for growth model selection
Literature surrounding the statistical modeling of childhood growth data involves a diverse set of potential models from which investigators can choose. However, the lack of a comprehensive framework for compa...
