56 Result(s)

Article

Analysis of clinicopathological features and NAB2-STAT6 fusion variants of meningeal solitary fibrous tumor with ectopic salivary gland components in the cerebellopontine angle

Solitary fibrous tumors (SFTs) are rare mesenchymal tumors that can occur at any location. Since the identification of specific NAB2-STAT6 fusion in SFTs, the fusion gene variants, NAB2 exon 4-STAT6 exon 2/3 and

Takahiro Shirakura, Yuichi Yamada, Satoshi Nakata, Bunsho Asayama… in Virchows Archiv (2022)

Article

Pathological and molecular analysis of a composite lymphoma of mantle cell lymphoma and Epstein–Barr virus-positive follicular lymphoma

Composite lymphoma (CL) is a very rare clinical entity defined by the presence of two or more different subtypes of lymphoma in the same lymph node. We report a case of CL in a 78-year-old male presenting with...

Yuri Miyazawa, Akihiko Yokohama, Takuma Ishizaki… in International Journal of Hematology (2021)

Article

Adenocarcinoma with intraductal papillary mucinous neoplasm arising in a duodenal heterotopic pancreas: a case report

A woman in her 70 s was diagnosed with a tumor in her duodenal wall during a routine visit for diabetes. She subsequently underwent subtotal stomach-preserving pancreatoduodenectomy. Histologically, the tumor ...

Etsuko Hisanaga, Takaaki Sano, Norio Kubo… in Clinical Journal of Gastroenterology (2020)

Article

RELA fusion-positive ependymoma accompanied by extensive desmoplasia: a case report

We report a case of 33-year-old Japanese male who presented with a headache and visual disturbances. Magnetic resonance imaging revealed a large tumor in the left frontal lobe, measuring 7 cm in diameter, whic...

Tsuyoshi Fukushima, Takashi Ueda, Junko Hirato, Hiroaki Kataoka in Brain Tumor Pathology (2020)

Article

Central nervous system ganglioneuroblastoma harboring MYO5A-NTRK3 fusion

Central nervous system (CNS) ganglioneuroblastoma is a rare neuroectodermal neoplasm and little is known about its clinical and biological features. Herein, we report a pediatric case of CNS ganglioneuroblasto...

Jumpei Ito, Yoshiko Nakano, Haruko Shima, Tomoru Miwa… in Brain Tumor Pathology (2020)

Article

Secondary INI1-deficient rhabdoid tumors of the central nervous system: analysis of four cases and literature review

Atypical teratoid/rhabdoid tumors (AT/RT) are rare, highly malignant neoplasms of the central nervous system that predominantly occur in infants, and are characterized by the presence of rhabdoid cells and ina...

Sumihito Nobusawa, Satoshi Nakata, Yuka Yoshida, Tatsuya Yamazaki… in Virchows Archiv (2020)

Article

Anaplastic pleomorphic xanthoastrocytoma associated with an H3G34 mutation: a case report with review of literature

Here, we report a rare case of anaplastic pleomorphic xanthoastrocytoma (PXA) associated with an H3G34 mutation. A 12-year-old male presented with loss of appetite, vomiting, headache, and a generalized seizur...

Shoh Sasaki, Ran Tomomasa, Sumihito Nobusawa, Junko Hirato… in Brain Tumor Pathology (2019)

Article

High-grade glioneuronal tumor with an ARHGEF2–NTRK1 fusion gene

Here, we report a highly unusual case of high-grade glioneuronal tumor with a neurotrophic tropomyosin receptor kinase (NTRK) fusion gene. A 13-year-old girl presented with headache and vomiting and MRI detected ...

Kazuhiko Kurozumi, Yoshiko Nakano, Joji Ishida, Takehiro Tanaka… in Brain Tumor Pathology (2019)

Article

Multiplex ligation-dependent probe amplification analysis is useful for detecting a copy number gain of the FGFR1 tyrosine kinase domain in dysembryoplastic neuroepithelial tumors

Dysembryoplastic neuroepithelial tumors (DNTs) are slow-growing glioneuronal tumors, and their genetic backgrounds are getting unveiled. Recently, fibroblast growth factor receptor 1 internal tandem duplication (

Nozomi Matsumura, Sumihito Nobusawa, Junko Ito… in Journal of Neuro-Oncology (2019)

Article

Review of ependymomas: assessment of consensus in pathological diagnosis and correlations with genetic profiles and outcome

We focused on histological and immunohistochemical characteristics of ependymoma (EPN) with molecular profiles to develop more reproducible criteria of the diagnosis. Three expert neuropathologists reviewed th...

Atsushi Sasaki, Junko Hirato, Takanori Hirose, Kohei Fukuoka… in Brain Tumor Pathology (2019)

Article

Collision of metastatic malignant melanoma and acute myelogenous leukemia in the bone marrow

Nobuhiko Kobayashi, Hiroaki Shimizu, Junko Hirato… in International Journal of Hematology (2018)

Article

Histone H3 K27M mutations in adult cerebellar high-grade gliomas

Adult cerebellar high-grade gliomas (HGG) are rare and their molecular basis has not been fully elucidated. Although a diffuse midline glioma H3 K27M-mutant, a recently characterized variant of HGG, was report...

Satoshi Nakata, Sumihito Nobusawa, Tatsuya Yamazaki, Tadashi Osawa… in Brain Tumor Pathology (2017)

Article

Multiple intradural-extramedullary spinal ependymomas including tumors with different histological features

We report a rare case with multiple intradural-extramedullary spinal ependymomas with different histological features.

Akira Honda, Yoichi Iizuka, Junko Hirato, Hiroki Kiyohara… in European Spine Journal (2017)

Article

Atypical teratoid/rhabdoid tumor in the sella turcica of an elderly female with a distinct vascular pattern and genetic alterations

Sumihito Nobusawa, Satoshi Nakata, Junko Hirato, Takahiro Kawashima… in Virchows Archiv (2016)